MRI methods are widely used to follow the pathological evolution of multiple sclerosis in life
and its modification by treatment. To date, measures of the number and volume of …

Brain atrophy has emerged as a clinically relevant component of disease progression in
multiple sclerosis. Progressive loss of brain tissue bulk can be detected in vivo in a sensitive …

Two prior double‐blind, placebo‐controlled, randomized trials demonstrated that glatiramer
acetate (GA) reduces relapse rates in patients with relapsing remitting multiple sclerosis …

Longitudinal neuroimaging (LNI) studies are rapidly becoming more prevalent and growing
in size. Today, no standardized computational tools exist for the analysis of LNI data and …

Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system
characterized by focal or diffuse inflammation, demyelination, axonal loss and …

Objective: To assess the time course of brain atrophy and the difference across clinical
subtypes in multiple sclerosis (MS). Methods: The percent brain volume change (PBVC) was …

Multiple sclerosis (MS) is the most common neurological immune-mediated disease leading
to disability in young adults. The outcome of the disease is unpredictable, and over time …

Despite important advances in the treatment of multiple sclerosis (MS) over recent years, the
introduction of several disease-modifying therapies (DMTs), the burden of progressive …

Women are more susceptible to a variety of autoimmune diseases including systemic lupus
erythematosus (SLE), multiple sclerosis (MS), primary biliary cirrhosis, rheumatoid arthritis …

MR offers by far the most sensitive technique for detecting multiple sclerosis (MS) lesions
and has proved to be an important paraclinical tool for diagnosing MS and monitoring …