[HTML][HTML] Recent advance in biological responsive nanomaterials for biosensing and molecular imaging application

Z Jiang, X Han, C Zhao, S Wang, X Tang - International Journal of …, 2022 - mdpi.com
In recent decades, as a subclass of biomaterials, biologically sensitive nanoparticles have
attracted increased scientific interest. Many of the demands for physiologically responsive …

The role of CREB and BDNF in neurobiology and treatment of Alzheimer's disease

M Amidfar, J de Oliveira, E Kucharska, J Budni, YK Kim - Life sciences, 2020 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia worldwide. β-amyloid
peptide (Aβ) is currently assumed to be the main cause of synaptic dysfunction and cognitive …

[HTML][HTML] Brain-derived neurotrophic factor: a key molecule for memory in the healthy and the pathological brain

M Miranda, JF Morici, MB Zanoni… - Frontiers in cellular …, 2019 - frontiersin.org
Brain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes
related to learning and memory. The expression of BDNF is highly regulated, and can lead …

Depression—an underrecognized target for prevention of dementia in Alzheimer's disease

FS Dafsari, F Jessen - Translational psychiatry, 2020 - nature.com
It is broadly acknowledged that the onset of dementia in Alzheimer's disease (AD) may be
modifiable by the management of risk factors. While several recent guidelines and …

Serotonin and brain function: a tale of two receptors

RL Carhart-Harris, DJ Nutt - Journal of psychopharmacology, 2017 - journals.sagepub.com
Previous attempts to identify a unified theory of brain serotonin function have largely failed to
achieve consensus. In this present synthesis, we integrate previous perspectives with new …

[PDF][PDF] Brain-derived neurotrophic factor and its clinical implications

S Bathina, UN Das - Archives of medical science, 2015 - termedia.pl
Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal survival and
growth, serves as a neurotransmitter modulator, and participates in neuronal plasticity …

Serotonin and neuroplasticity–links between molecular, functional and structural pathophysiology in depression

C Kraus, E Castrén, S Kasper… - … & Biobehavioral Reviews, 2017 - Elsevier
Serotonin modulates neuroplasticity, especially during early life, and dysfunctions in both
systems likewise contribute to pathophysiology of depression. Recent findings demonstrate …

From stress to inflammation and major depressive disorder: a social signal transduction theory of depression.

GM Slavich, MR Irwin - Psychological bulletin, 2014 - psycnet.apa.org
Major life stressors, especially those involving interpersonal stress and social rejection, are
among the strongest proximal risk factors for depression. In this review, we propose a …

[HTML][HTML] Major depression: one brain, one disease, one set of intertwined processes

EV Filatova, MI Shadrina, PA Slominsky - Cells, 2021 - mdpi.com
Major depressive disorder (MDD) is a heterogeneous disease affecting one out of five
individuals and is the leading cause of disability worldwide. Presently, MDD is considered a …

Skeletal muscle as an endocrine organ: PGC-1α, myokines and exercise

S Schnyder, C Handschin - Bone, 2015 - Elsevier
An active lifestyle is crucial to maintain health into old age; inversely, sedentariness has
been linked to an elevated risk for many chronic diseases. The discovery of myokines …