The clinical success of cancer immune checkpoint blockade (ICB) has refocused attention
on tumor-infiltrating lymphocytes (TILs) across cancer types. The outcome of immune …

The advent of single-cell RNA sequencing (scRNA-seq) has provided insight into the tumour
immune microenvironment (TIME). This review focuses on the application of scRNA-seq in …

The current tumour-node-metastasis (TNM) staging system alone cannot provide adequate
information for prognosis and adjuvant chemotherapy benefits in patients with gastric cancer …

Tumor microenvironment (TME) cells constitute a vital element of tumor tissue. Increasing
evidence has elucidated their clinicopathologic significance in predicting outcomes and …

Gastric cancer (GC) is one of the leading causes of cancer-related deaths and shows high
levels of heterogeneity. The development of a specific prognostic model is important if we …

Background TP53 mutation is the most common mutation in hepatocellular carcinoma
(HCC), and it affects the progression and prognosis of HCC. We investigated how TP53 …

Abstract Background Circular RNAs (circRNAs) are a class of noncoding RNAs (ncRNAs)
and can modulate gene expression by binding to miRNAs; further, circRNAs have been …

The tumor microenvironment (TME) chiefly consists of tumor cells and tumor-infiltrating
immune cells admixed with the stromal component. A recent clinical trial has shown that the …

Immunotherapies play critical roles in cancer treatment. However, given that only a few
patients respond to immune checkpoint blockades and other immunotherapeutic strategies …

The tumor immune microenvironment (TIME) is associated with tumor prognosis and
immunotherapy response. Here we develop and validate a CT-based radiomics score (RS) …