Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

H Cao, L Duan, Y Zhang, J Cao, K Zhang - Signal transduction and …, 2021‏ - nature.com
Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

Progress of microfluidic hydrogel‐based scaffolds and organ‐on‐chips for the cartilage tissue engineering

H Tolabi, N Davari, M Khajehmohammadi… - Advanced …, 2023‏ - Wiley Online Library
Cartilage degeneration is among the fundamental reasons behind disability and pain across
the globe. Numerous approaches have been employed to treat cartilage diseases …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G **… - Chemical …, 2017‏ - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Manufacturing of hydrogel biomaterials with controlled mechanical properties for tissue engineering applications

A Vedadghavami, F Minooei, MH Mohammadi… - Acta biomaterialia, 2017‏ - Elsevier
Hydrogels have been recognized as crucial biomaterials in the field of tissue engineering,
regenerative medicine, and drug delivery applications due to their specific characteristics …

Advances in gelatin bioinks to optimize bioprinted cell functions

S Asim, TA Tabish, U Liaqat, IT Ozbolat… - Advanced healthcare …, 2023‏ - Wiley Online Library
Gelatin is a widely utilized bioprinting biomaterial due to its cell‐adhesive and enzymatically
cleavable properties, which improve cell adhesion and growth. Gelatin is often covalently …

Effect of microporosity on scaffolds for bone tissue engineering

K Zhang, Y Fan, N Dunne, X Li - Regenerative biomaterials, 2018‏ - academic.oup.com
Microporosity has a critical role in improving the osteogenesis of scaffolds for bone tissue
engineering. Although the exact mechanism, by which it promotes new bone formation, is …

25th anniversary article: Rational design and applications of hydrogels in regenerative medicine

N Annabi, A Tamayol, JA Uquillas, M Akbari… - Advanced …, 2014‏ - Wiley Online Library
Hydrogels are hydrophilic polymer‐based materials with high water content and physical
characteristics that resemble the native extracellular matrix. Because of their remarkable …

Omnidirectional printing of 3D microvascular networks

W Wu, A DeConinck, JA Lewis - Advanced materials, 2011‏ - Wiley Online Library
Nature is replete with examples of microvascular systems that enable efficient fluid flow and
distribution for autonomic healing, cooling, and energy harvesting. Emulating these systems …

Microfluidic fabrication of microengineered hydrogels and their application in tissue engineering

BG Chung, KH Lee, A Khademhosseini, SH Lee - Lab on a Chip, 2012‏ - pubs.rsc.org
Microfluidic technologies are emerging as an enabling tool for various applications in tissue
engineering and cell biology. One emerging use of microfluidic systems is the generation of …

Microfluidic techniques for development of 3D vascularized tissue

A Hasan, A Paul, NE Vrana, X Zhao, A Memic… - Biomaterials, 2014‏ - Elsevier
Abstract Development of a vascularized tissue is one of the key challenges for the
successful clinical application of tissue engineered constructs. Despite the significant efforts …