Gold complexes in anticancer therapy: From new design principles to particle‐based delivery systems
The discovery of the medicinal properties of gold complexes has fuelled the design and
synthesis of new anticancer metallodrugs, which have received special attention due to their …
synthesis of new anticancer metallodrugs, which have received special attention due to their …
[HTML][HTML] A review on metal complexes and its anti-cancer activities: Recent updates from in vivo studies
Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …
New copper complexes inducing bimodal death through apoptosis and autophagy in A549 cancer cells
Abstract Two copper complexes, Cu1 (CuL 1 Cl 2, L 1= 2-(6, 7-dimethoxyisoquinolin-1-yl)
aniline) and Cu2 (CuL 2 Cl 2, L 2= 2-(6-methoxyisoquinolin-1-yl) aniline), were synthesized …
aniline) and Cu2 (CuL 2 Cl 2, L 2= 2-(6-methoxyisoquinolin-1-yl) aniline), were synthesized …
Novel zinc (II)− curcumin molecular probes bearing berberine and jatrorrhizine derivatives as potential mitochondria-targeting anti-neoplastic drugs
SH Zhang, ZF Wang, H Tan - European Journal of Medicinal Chemistry, 2022 - Elsevier
Berberine and jatrorrhizine are major bioactive components that are emerging as potential
anti-cancer drugs. However, no zinc (II)–berberine/jatrorrhizine–curcumin compounds have …
anti-cancer drugs. However, no zinc (II)–berberine/jatrorrhizine–curcumin compounds have …
Coordination behavior of cocaine toward d-block metal ions: synthesis, spectral analysis, density functional theory (DFT) studies, and chemotherapeutic activity
The exploration of novel bioactive metallopharmaceuticals for the treatment of diseases
such as microbial infections or cancer, with a focus on reducing side effects and drug …
such as microbial infections or cancer, with a focus on reducing side effects and drug …
Advances in anticancer alkaloid-derived metallo-chemotherapeutic agents in the last decade: Mechanism of action and future prospects
Metal-based complexes have occupied a pioneering niche in the treatment of many chronic
diseases, including various types of cancers. Despite the phenomenal success of cisplatin …
diseases, including various types of cancers. Despite the phenomenal success of cisplatin …
Therapeutic strategies for targeting telomerase in cancer
X Chen, WJ Tang, JB Shi, MM Liu… - Medicinal research …, 2020 - Wiley Online Library
Telomere and telomerase play important roles in abnormal cell proliferation, metastasis,
stem cell maintenance, and immortalization in various cancers. Therefore, designing of …
stem cell maintenance, and immortalization in various cancers. Therefore, designing of …
Ni (II), Cu (II) and Zn (II) complexes with the 1-trifluoroethoxyl-2, 9, 10-trimethoxy-7-oxoaporphine ligand simultaneously target microtubules and mitochondria for …
LS Liao, Y Chen, ZY Mo, C Hou, GF Su… - Inorganic Chemistry …, 2021 - pubs.rsc.org
Metal complexes of [NiL2 (NO3) 2](1),[CuL2 (NO3) 2](2) and [ZnL2 (NO3) 2](3) with the 1-
trifluoroethoxyl-2, 9, 10-trimethoxy-7-oxoaporphine (L) ligand were synthesized. We …
trifluoroethoxyl-2, 9, 10-trimethoxy-7-oxoaporphine (L) ligand were synthesized. We …
New gold (III) chlorophenyl terpyridine complex: Biomolecular interactions and anticancer activity against human oral squamous cell carcinoma
S Radisavljević, A Kesić, D Ćoćić… - Applied …, 2023 - Wiley Online Library
In this work we synthesized new monofunctional gold (III) complex [Au (Cl‐Ph‐tpy) Cl] Cl2
(Cl‐Ph‐tpy= 4′‐[4‐chlorophenyl]‐2, 2′: 6′, 2 ″‐terpyridine). This complex was …
(Cl‐Ph‐tpy= 4′‐[4‐chlorophenyl]‐2, 2′: 6′, 2 ″‐terpyridine). This complex was …
Impact of Drought and Flooding on Alkaloid Production in Annona crassiflora Mart
ABM Honório, I De-la-Cruz-Chacón… - Horticulturae, 2021 - mdpi.com
The Brazilian Cerrado is the second largest Brazilian biome. In recent decades, a reduction
in rainfall has indicated an extension of the dry season. Among the many native species of …
in rainfall has indicated an extension of the dry season. Among the many native species of …