TeraChem was born in 2008 with the goal of providing fast on‐the‐fly electronic structure
calculations to facilitate ab initio molecular dynamics studies of large biochemical systems …

The use of mechanical forces to chemically transform polymers dates back decades. In
recent years, the use of mechanochemistry to direct constructive transformations in polymers …

This paper results from a round table discussion at the CCTC2018 Conference in Changsha
City, Hunan, China, in December 2018. It presents a report on the status, prospects, and …

The development of force-responsive molecules called mechanophores is a central
component of the field of polymer mechanochemistry. Mechanophores enable the design …

Conspectus When one brings “polymeric materials” and “mechanical action” into the same
conversation, the topic of this discussion might naturally focus on everyday circumstances …

This paper reviews the history of mechanochemistry. It begins with prehistoric times, when
reactions could be initiated during grinding and rubbing accidentally, and follows the main …

Biological systems sense and respond to mechanical stimuli in a complex manner. In an
effort to develop synthetic materials that transduce mechanical force into multifold changes …

Engineering applications of synthetic polymers are widespread due to their availability,
processability, low density, and diversity of mechanical properties (Figure 1a). Despite their …

Covalent mechanochemistry within bulk polymers typically occurs with irreversible
deformation of the parent material. Here we show that embedding mechanophores into an …

In the following section, we will recapitulate selected experimental milestones through the
eyes of the theoretician, which, in our opinion, significantly advanced the field of covalent …