Role of the gut–brain axis in energy and glucose metabolism

HR Wachsmuth, SN Weninger, FA Duca - Experimental & molecular …, 2022 - nature.com
The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …

[HTML][HTML] Free fatty acid receptors in health and disease

I Kimura, A Ichimura, R Ohue-Kitano… - Physiological …, 2019 - journals.physiology.org
Fatty acids are metabolized and synthesized as energy substrates during biological
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …

Fatty acid transport and signaling: mechanisms and physiological implications

D Samovski, M Jacome-Sosa… - Annual review of …, 2023 - annualreviews.org
Long-chain fatty acids (FAs) are components of plasma membranes and an efficient fuel
source and also serve as metabolic regulators through FA signaling mediated by membrane …

Ghrelin, CCK, GLP-1, and PYY (3–36): secretory controls and physiological roles in eating and glycemia in health, obesity, and after RYGB

RE Steinert, C Feinle-Bisset, L Asarian… - Physiological …, 2017 - journals.physiology.org
The efficacy of Roux-en-Y gastric-bypass (RYGB) and other bariatric surgeries in the
management of obesity and type 2 diabetes mellitus and novel developments in …

Gut-brain axis and migraine headache: a comprehensive review

M Arzani, SR Jahromi, Z Ghorbani, F Vahabizad… - The journal of headache …, 2020 - Springer
The terminology “gut-brain axis “points out a bidirectional relationship between the GI
system and the central nervous system (CNS). To date, several researches have shown that …

Fatty acid-induced lipotoxicity in pancreatic beta-cells during development of type 2 diabetes

YS Oh, GD Bae, DJ Baek, EY Park… - Frontiers in …, 2018 - frontiersin.org
Type 2 diabetes is caused by chronic insulin resistance and progressive decline in beta-cell
function. Optimal beta-cell function and mass is essential for glucose homeostasis and beta …

Enteroendocrine cells: chemosensors in the intestinal epithelium

FM Gribble, F Reimann - Annual review of physiology, 2016 - annualreviews.org
The enteroendocrine system orchestrates how the body responds to the ingestion of foods,
employing a diversity of hormones to fine-tune a wide range of physiological responses both …

Protective effects of omega-3 fatty acids in cancer-related complications

RDS Freitas, MM Campos - Nutrients, 2019 - mdpi.com
Omega-3 polyunsaturated fatty acids (PUFAs) are considered immunonutrients and are
commonly used in the nutritional therapy of cancer patients due to their ample biological …

Therapeutic potential of ectopic olfactory and taste receptors

SJ Lee, I Depoortere, H Hatt - Nature Reviews Drug Discovery, 2019 - nature.com
Olfactory and taste receptors are expressed primarily in the nasal olfactory epithelium and
gustatory taste bud cells, where they transmit real-time sensory signals to the brain …

Gut feelings: the emerging biology of gut–brain communication

EA Mayer - Nature reviews neuroscience, 2011 - nature.com
The concept that the gut and the brain are closely connected, and that this interaction plays
an important part not only in gastrointestinal function but also in certain feeling states and in …