Use of Bombyx mori silk fibroin in tissue engineering: From cocoons to medical devices, challenges, and future perspectives

A Bucciarelli, A Motta - Biomaterials Advances, 2022 - Elsevier
Silk fibroin has become a prominent material in tissue engineering (TE) over the last 20
years with almost 10,000 published works spanning in all the TE applications, from skeleton …

Enzymatic Degradation of Bombyx mori Silk Materials: A Review

C Guo, C Li, DL Kaplan - Biomacromolecules, 2020 - ACS Publications
As a biomaterial, silk presents unique features with a combination of excellent mechanical
properties, biocompatibility, and biodegradability. The biodegradability aspects of silk …

Silk microneedle patch capable of on‐demand multidrug delivery to the brain for glioblastoma treatment

Z Wang, Z Yang, J Jiang, Z Shi, Y Mao… - Advanced …, 2022 - Wiley Online Library
Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Surgery
followed by chemotherapy and radiotherapy remains the standard treatment strategy for …

Thermoplastic moulding of regenerated silk

C Guo, C Li, HV Vu, P Hanna, A Lechtig, Y Qiu, X Mu… - Nature Materials, 2020 - nature.com
Early insights into the unique structure and properties of native silk suggested that β-sheet
nanocrystallites in silk would degrade prior to melting when subjected to thermal processing …

A biodegradable and stretchable protein‐based sensor as artificial electronic skin for human motion detection

C Hou, Z Xu, W Qiu, R Wu, Y Wang, Q Xu, XY Liu… - Small, 2019 - Wiley Online Library
Due to the natural biodegradability and biocompatibility, silk fibroin (SF) is one of the ideal
platforms for on‐skin and implantable electronic devices. However, the development of SF …

A silk-based self-adaptive flexible opto-electro neural probe

Y Zhou, C Gu, J Liang, B Zhang, H Yang… - Microsystems & …, 2022 - nature.com
The combination of optogenetics and electrophysiological recording enables high-precision
bidirectional interactions between neural interfaces and neural circuits, which provides a …

Biomimicking antibacterial opto‐electro sensing sutures made of regenerated silk proteins

M Liu, Y Zhang, K Liu, G Zhang, Y Mao… - Advanced …, 2021 - Wiley Online Library
Surgical sutures play an important role across a wide range of medical treatments and a
wide variety exist, differing in strength, size, composition, and performance. Recently …

[HTML][HTML] Engineering silk materials: From natural spinning to artificial processing

C Guo, C Li, X Mu, DL Kaplan - Applied Physics Reviews, 2020 - pubs.aip.org
Silks spun by the arthropods are “ancient” materials historically utilized for fabricating high-
quality textiles. Silks are natural protein-based biomaterials with unique physical and …

In situ regulation of macrophage polarization to enhance osseointegration under diabetic conditions using injectable silk/sitagliptin gel scaffolds

G **ang, K Liu, T Wang, X Hu, J Wang, Z Gao… - Advanced …, 2021 - Wiley Online Library
As a chronic inflammatory disease, diabetes mellitus creates a proinflammatory
microenvironment around implants, resulting in a high rate of implant loosening or failure in …

Tissue/Organ Adaptable Bioelectronic Silk‐Based Implants

Z Zhu, Z Yan, S Ni, H Yang, Y **e, X Wang… - Advanced …, 2024 - Wiley Online Library
Implantable bioelectronic devices, designed for both monitoring and modulating living
organisms, require functional and biological adaptability. Pure silk is innovatively employed …