Post-traumatic stress disorder (PTSD) can become a chronic and severely disabling
condition resulting in a reduced quality of life and increased economic burden. The disorder …

Stress is defined as an adverse condition that disturbs the homeostasis of the body and
activates adaptation responses. Among the many pathways and mediators involved …

John Briere and Catherine Scott′ s Principles of Trauma Therapy, Third Edition is both
comprehensive in scope and highly practical in application. This best selling text provides a …

Post-traumatic stress disorder (PTSD) is the only major mental disorder for which a cause is
considered to be known: that is, an event that involves threat to the physical integrity of …

Resilience is the ability to adapt successfully in the face of stress and adversity. Stressful life
events, trauma, and chronic adversity can have a substantial impact on brain function and …

Neuropeptides are important mediators both within the nervous system and between
neurons and other cell types. Neuropeptides such as substance P, calcitonin gene-related …

The gut–brain axis refers to the bidirectional communication between the gut and the brain.
Four information carriers (vagal and spinal afferent neurons, immune mediators such as …

There is significant variation in the way individuals react and respond to extreme stress and
adversity. While some individuals develop psychiatric conditions such as posttraumatic …

Major depression, with its strikingly high prevalence, is the most common cause of disability
in communities of Western type, according to data of the World Health Organization. Stress …

Introduction: Anxiety disorders are among the most prevalent and disabling psychiatric
disorders in the United States and worldwide. Basic research has provided critical insights …