Enteric nervous system: sensory transduction, neural circuits and gastrointestinal motility

NJ Spencer, H Hu - Nature reviews Gastroenterology & hepatology, 2020 - nature.com
The gastrointestinal tract is the only internal organ to have evolved with its own independent
nervous system, known as the enteric nervous system (ENS). This Review provides an …

The hologenome concept of evolution after 10 years

E Rosenberg, I Zilber-Rosenberg - Microbiome, 2018 - Springer
The holobiont (host with its endocellular and extracellular microbiome) can function as a
distinct biological entity, an additional organismal level to the ones previously considered …

Simple animal models for microbiome research

AE Douglas - Nature Reviews Microbiology, 2019 - nature.com
The health and fitness of animals, including humans, are influenced by the presence and
composition of resident microbial communities. The development of rational microbial …

An introduction to phylosymbiosis

SJ Lim, SR Bordenstein - Proceedings of the Royal …, 2020 - royalsocietypublishing.org
Phylosymbiosis was recently formulated to support a hypothesis-driven framework for the
characterization of a new, cross-system trend in host-associated microbiomes. Defining …

The enteric nervous system in gastrointestinal disease etiology

AM Holland, AC Bon-Frauches, D Keszthelyi… - Cellular and Molecular …, 2021 - Springer
A highly conserved but convoluted network of neurons and glial cells, the enteric nervous
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …

A complete biomechanical model of Hydra contractile behaviors, from neural drive to muscle to movement

H Wang, J Swore, S Sharma… - Proceedings of the …, 2023 - National Acad Sciences
How does neural activity drive muscles to produce behavior? The recent development of
genetic lines in Hydra that allow complete calcium imaging of both neuronal and muscle …

Harnessing the power of model organisms to unravel microbial functions in the coral holobiont

G Puntin, M Sweet, S Fraune, M Medina… - Microbiology and …, 2022 - Am Soc Microbiol
Stony corals build the framework of coral reefs, ecosystems of immense ecological and
economic importance. The existence of these ecosystems is threatened by climate change …

[HTML][HTML] Enteric neuroimmune interactions coordinate intestinal responses in health and disease

H Wang, JPP Foong, NL Harris, JC Bornstein - Mucosal immunology, 2022 - Elsevier
The enteric nervous system (ENS) of the gastrointestinal (GI) tract interacts with the local
immune system bidirectionally. Recent publications have demonstrated that such …

Why do hosts malfunction without microbes? Missing benefits versus evolutionary addiction

TJ Hammer - Trends in Microbiology, 2024 - cell.com
Microbes are widely recognized to be vital to host health. This new consensus rests, in part,
on experiments showing how hosts malfunction when microbes are removed. More and …

[HTML][HTML] Multiple neuronal populations control the eating behavior in Hydra and are responsive to microbial signals

C Giez, D Pinkle, Y Giencke, J Wittlieb, E Herbst… - Current Biology, 2023 - cell.com
Although recent studies indicate the impact of microbes on the central nervous systems and
behavior, it remains unclear how the relationship between the functionality of the nervous …