Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications

F Zhang, RI Lau, Q Liu, Q Su, FKL Chan… - Nature Reviews …, 2023 - nature.com
The gastrointestinal tract is involved in coronavirus disease 2019 (COVID-19) caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gut microbiota has …

The gut microbiome and hypertension

JA O'Donnell, T Zheng, G Meric… - Nature Reviews …, 2023 - nature.com
A large body of evidence has emerged in the past decade supporting a role for the gut
microbiome in the regulation of blood pressure. The field has moved from association to …

Association between gut microbiota and preeclampsia-eclampsia: a two-sample Mendelian randomization study

P Li, H Wang, L Guo, X Gou, G Chen, D Lin, D Fan… - BMC medicine, 2022 - Springer
Background Several recent observational studies have reported that gut microbiota
composition is associated with preeclampsia. However, the causal effect of gut microbiota …

Causal relationship between gut microbiota and cancers: a two-sample Mendelian randomisation study

Y Long, L Tang, Y Zhou, S Zhao, H Zhu - BMC medicine, 2023 - Springer
Background Evidence from observational studies and clinical trials suggests that the gut
microbiota is associated with cancer. However, the causal association between gut …

Non-alcoholic fatty liver disease: the interplay between metabolism, microbes and immunity

H Tilg, TE Adolph, M Dudek, P Knolle - Nature metabolism, 2021 - nature.com
Non-alcoholic fatty liver disease (NAFLD) has emerged pandemically across the globe and
particularly affects patients with obesity and type 2 diabetes. NAFLD is a complex systemic …

Microbiome and cancer

N Cullin, CA Antunes, R Straussman… - Cancer cell, 2021 - cell.com
The human microbiome constitutes a complex multikingdom community that symbiotically
interacts with the host across multiple body sites. Host-microbiome interactions impact …

Causal relationship between gut microbiota and autoimmune diseases: a two-sample Mendelian randomization study

Q Xu, JJ Ni, BX Han, SS Yan, XT Wei, GJ Feng… - Frontiers in …, 2022 - frontiersin.org
Background Growing evidence has shown that alterations in gut microbiota composition are
associated with multiple autoimmune diseases (ADs). However, it is unclear whether these …

Oxidative stress gene expression, DNA methylation, and gut microbiota interaction trigger Crohn's disease: a multi-omics Mendelian randomization study

S Xu, X Li, S Zhang, C Qi, Z Zhang, R Ma, L **ang… - BMC medicine, 2023 - Springer
Background Oxidative stress (OS) is a key pathophysiological mechanism in Crohn's
disease (CD). OS-related genes can be affected by environmental factors, intestinal …

Role of the gut microbiota in anticancer therapy: from molecular mechanisms to clinical applications

LY Zhao, JX Mei, G Yu, L Lei, WH Zhang… - … and Targeted Therapy, 2023 - nature.com
In the past period, due to the rapid development of next-generation sequencing technology,
accumulating evidence has clarified the complex role of the human microbiota in the …

Genetic correlations between Alzheimer's disease and gut microbiome genera

D Cammann, Y Lu, MJ Cummings, ML Zhang… - Scientific Reports, 2023 - nature.com
A growing body of evidence suggests that dysbiosis of the human gut microbiota is
associated with neurodegenerative diseases like Alzheimer's disease (AD) via …