Recent advances in the surface functionalization of PLGA-based nanomedicines

MM El-Hammadi, JL Arias - Nanomaterials, 2022 - mdpi.com
Therapeutics are habitually characterized by short plasma half-lives and little affinity for
targeted cells. To overcome these challenges, nanoparticulate systems have entered into …

Review of approaches for increasing ophthalmic bioavailability for eye drop formulations

OL Lanier, MG Manfre, C Bailey, Z Liu, Z Sparks… - Aaps Pharmscitech, 2021 - Springer
Ophthalmic diseases represent a significant problem as over 2 billion people worldwide
suffer from vison impairment and blindness. Eye drops account for around 90% of …

Thymol-loaded PLGA nanoparticles: an efficient approach for acne treatment

C Folle, AM Marqués, N Díaz-Garrido, M Espina… - Journal of …, 2021 - Springer
Background Acne is a common skin disorder that involves an infection inside the hair follicle,
which is usually treated with antibiotics, resulting in unbalanced skin microbiota and …

[HTML][HTML] RETRACTED: Development of thermosensitive hydrogel of Amphotericin-B and Lactoferrin combination-loaded PLGA-PEG-PEI nanoparticles for potential …

SF Elhabal, SA Ghaffar, R Hager, NA Elzohairy… - 2023 - Elsevier
[email protected](MH Elkomy),[email protected](MA Khasawneh). Contents lists available at
ScienceDirect International Journal of Pharmaceutics: X journal homepage: www …

Development of lactoferrin-loaded liposomes for the management of dry eye disease and ocular inflammation

A López-Machado, N Díaz-Garrido, A Cano, M Espina… - Pharmaceutics, 2021 - mdpi.com
Dry eye disease (DED) is a high prevalent multifactorial disease characterized by a lack of
homeostasis of the tear film which causes ocular surface inflammation, soreness, and visual …

Development and optimization of Riluzole-loaded biodegradable nanoparticles incorporated in a mucoadhesive in situ gel for the posterior eye segment

G Esteruelas, L Halbaut, V Garcia-Torra… - International Journal of …, 2022 - Elsevier
Riluzole-loaded PLGA nanoparticles (RLZ-NPs) were developed to improve the
biopharmaceutical profile of RLZ after ocular administration. Moreover, RLZ-NPs were …

[HTML][HTML] Overcoming the cellular barriers and beyond: Recent progress on cell penetrating peptide modified nanomedicine in combating physiological and …

Y Liu, Z Zhao, M Li - Asian Journal of Pharmaceutical Sciences, 2022 - Elsevier
The complex physiological and pathological conditions form barriers against efficient drug
delivery. Cell penetrating peptides (CPPs), a class of short peptides which translocate drugs …

Recent development of nanomaterials for transdermal drug delivery

MY Leong, YL Kong, K Burgess, WF Wong, G Sethi… - Biomedicines, 2023 - mdpi.com
Nano-engineered medical products first appeared in the last decade. The current research
in this area focuses on develo** safe drugs with minimal adverse effects associated with …

[HTML][HTML] Development of topical eye-drops of lactoferrin-loaded biodegradable nanoparticles for the treatment of anterior segment inflammatory processes

A López-Machado, N Díaz, A Cano, M Espina… - International journal of …, 2021 - Elsevier
Ocular inflammation is one of the most common comorbidities associated to ophthalmic
surgeries and disorders. Since conventional topical ophthalmic treatments present …

Atorvastatin-loaded peptide amphiphiles against corneal neovascularization

E Sánchez-López, MJ Gómara, I Haro - Nanomedicine, 2023 - Taylor & Francis
Background: Corneal neovascularization is a sight-threatening disease. It can be treated
using antiangiogenic and anti-inflammatory compounds. Therefore, atorvastatin (ATV) …