National estimates of the participation of patients with cancer in clinical research studies based on commission on cancer accreditation data

JM Unger, LN Shulman, MA Facktor… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE National estimates of cancer clinical trial participation are nearly two decades old
and have focused solely on enrollment to treatment trials, which does not reflect the …

Multi-cancer early detection (MCED) tests: prioritizing equity from bench to bedside

SJ Miller, JR Sly, C Rolfo, P Mack… - Health Affairs …, 2024 - academic.oup.com
Multi-cancer early detection (MCED) tests are blood-based tests designed to screen for
signals of multiple cancers. There is growing interest and investment in examining the …

Racial and ethnic disparities in clinical trial enrollment among women with gynecologic cancer

W Khadraoui, CE Meade, FJ Backes… - JAMA network …, 2023 - jamanetwork.com
Importance Racial and ethnic disparities in clinical trial enrollment are unjust and hinder
development of new cancer treatments. Objective To examine the association of race and …

Defining a 'cells to society'research framework for appendiceal tumours

AN Holowatyj, MJ Overman, KI Votanopoulos… - Nature Reviews …, 2025 - nature.com
Tumours of the appendix—a vestigial digestive organ attached to the colon—are rare.
Although we estimate that around 3,000 new appendiceal cancer cases are diagnosed …

The US Food and Drug Administration dual mandate for rapid drug review and equity

RA Miksad, CA Ryals - JAMA Network Open, 2024 - jamanetwork.com
The metrics of success for oncology drug development and approval shifted with the shorter
time to approval associated with the US Food and Drug Administration (FDA) 2018 Real …

Are community oncology practices with or without clinical research programs different? A comparison of patient and practice characteristics

I Altomare, X Wang, M Kaur, JS Guadamuz… - JNCI Cancer …, 2024 - academic.oup.com
Background Expanding access to clinical trials in community settings is a potential approach
to addressing disparities in accrual of historically underrepresented populations. However …

Real-world treatment patterns and clinical outcomes in patients with radioiodine-refractory differentiated thyroid cancer (RAI-R DTC) treated with first line lenvatinib …

F Worden, O Rajkovic-Hooley, N Reynolds, G Milligan… - Endocrine, 2024 - Springer
Purpose Lenvatinib was approved for the treatment of patients with radioiodine-refractory
differentiated thyroid cancer (RAI-R DTC) in the United States (US) in 2015. The main …

Disparities in Clinical Trial Enrollment–Focus on CAR-T and Bispecific Antibody Therapies

N Islam, L Budvytyte, N Khera, T Hilal - Current Hematologic Malignancy …, 2025 - Springer
Disparities in Clinical Trial Enrollment– Focus on CAR-T and Bispecific Antibody Therapies |
Current Hematologic Malignancy Reports Skip to main content Springer Nature Link Account …

Research protocol for bridging research, accurate information and dialogue (BRAID)—clinical trials: a mixed-methods study of a community-based intervention to …

DN Gutnick, P Lozano, S Rodriguez Martinez… - Frontiers in Public …, 2024 - frontiersin.org
Cultural beliefs, personal experiences, and historic abuses within the healthcare system—
rooted in structural racism—all contribute to community distrust in science and medicine …

Clinical Trials—Real-World Data to Build a Future for Our Patients

CC Fahey, WK Rathmell - Journal of Clinical Oncology, 2024 - ascopubs.org
The first experimental use of chemotherapy was conducted in 1942 using nitrogen mustard
to treat non-Hodgkin lymphoma, 1, 2 marking the beginning of modern chemotherapy …