BACKGROUND During early mammalian brain development, transient neurons and circuits
form the scaffold for the development of neuronal networks. In the immature cerebral cortex …

Subjective tinnitus is the conscious perception of sound in the absence of any acoustic
source. The literature suggests various tinnitus mechanisms, most of which invoke changes …

Animal studies of neurodevelopment have shown that recordings of intrinsic cortical activity
evolve from synchronized and high amplitude to sparse and low amplitude as plasticity …

Different types of spiral ganglion neurons (SGNs) are essential for auditory perception by
transmitting complex auditory information from hair cells (HCs) to the brain. Here, we use …

Neurons in the develo** auditory system exhibit spontaneous bursts of activity before
hearing onset. How this intrinsically generated activity influences development remains …

In order to accurately process incoming sensory stimuli, neurons must be organized into
functional networks, with both genetic and environmental factors influencing the precise …

Spontaneous electrical activity of neurons in develo** sensory systems promotes their
maturation and proper connectivity. In the auditory system, spontaneous activity of cochlear …

Disturbed neuronal activity in neuropsychiatric pathologies emerges during development
and might cause multifold neuronal dysfunction by interfering with apoptosis, dendritic …

Cochlear synaptopathy produced by exposure to noise levels that cause only transient
auditory threshold elevations is a condition that affects many people and is believed to …

Spontaneous electrical activity is a common feature of sensory systems during early
development. This sensory-independent neuronal activity has been implicated in promoting …