Advances in the Catalytic Asymmetric Synthesis of Atropisomeric Hexatomic N‐Heterobiaryls

DJ Cheng, YD Shao - Advanced Synthesis & Catalysis, 2020 - Wiley Online Library
Axially chiral hexatomic N‐heterobiaryls are among the most important class of structures
with extensive utility in asymmetric catalysis as chiral ligands and organocatalysts, as …

Organocatalytic Atroposelective Dynamic Kinetic Resolution Involving Ring Manipulations

Q Shi, F Fang, DJ Cheng - Advanced Synthesis & Catalysis, 2024 - Wiley Online Library
Axially chiral architectures exist widely in natural products, biologically relevant molecules,
chiral ligands and catalysts as well as functional materials. Therefore, catalytic asymmetric …

Enantiodivergent Kinetic Resolution of 1, 1′‐Biaryl‐2, 2′‐Diols and Amino Alcohols by Dipeptide‐Phosphonium Salt Catalysis Inspired by the Atherton–Todd …

S Fang, JP Tan, J Pan, H Zhang, Y Chen… - Angewandte Chemie …, 2021 - Wiley Online Library
A highly enantiodivergent organocatalytic method is disclosed for the synthesis of
atropisomeric biaryls via kinetic resolution inspired by a dipeptide‐phosphonium salt …

Combined Dynamic Kinetic Resolution and C− H Functionalization for Facile Synthesis of Non‐Biaryl‐Atropisomer‐Type Axially Chiral Organosilanes

Z Li, X Wang, YM Cui, JH Ma, LL Fang… - … A European Journal, 2021 - Wiley Online Library
Although asymmetric C− H functionalization has been available for the synthesis of
structurally diverse molecules, catalytic dynamic kinetic resolution (DKR) approaches to …

Practical and scalable kinetic resolution of BINOLs mediated by a chiral counterion

BA Jones, T Balan, JD Jolliffe, CD Campbell… - Angewandte …, 2019 - Wiley Online Library
BINOLs are valuable and widely used building blocks, chiral ligands, and catalysts that are
effective across a remarkable range of different chemical transformations. Here we …

Kinetic and Dynamic Kinetic Resolution by Dual Catalysis

GL Thejashree, E Doris, E Gravel… - European Journal of …, 2022 - Wiley Online Library
Kinetic resolution is one of the most common methods to access enantiomerically enriched
compounds. In this method, the resolution is based on the existing difference in reaction …

Continuous‐Flow Dynamic Kinetic Resolution of Racemic Alcohols by Lipase–Oxovanadium Cocatalysis

K Higashio, S Katsuragi, D Kundu… - European Journal of …, 2020 - Wiley Online Library
A continuous‐flow dynamic kinetic resolution of racemic secondary alcohols was carried out
using a single column reactor packed with a mixture of immobilized lipase and an …

In Situ Structural Determination of a Homogeneous Ruthenium Racemization Catalyst and Its Activated Intermediates Using X‐Ray Absorption Spectroscopy

KPJ Gustafson, A Guðmundsson… - … A European Journal, 2020 - Wiley Online Library
The activation process of a known Ru‐catalyst, dicarbonyl (pentaphenylcyclopentadienyl)
ruthenium chloride, has been studied in detail using time resolved in situ X‐ray absorption …

Enantiodivergent Synthesis of Axially Chiral Biphenyls from σ‐Symmetric 1, 1'‐Biphenyl‐2, 6‐diol Derivatives by Single Lipase‐Catalyzed Acylative and Hydrolytic …

K Kasama, H Aoyama, S Akai - European Journal of Organic …, 2020 - Wiley Online Library
The enzymatic acylative desymmetrization of σ‐symmetric 2'‐halo‐1, 1'‐biphenyl‐2, 6‐diols
was achieved for the first time using commercially available Burkholderia cepacia lipase …