[HTML][HTML] Anandamide and other N-acylethanolamines: A class of signaling lipids with therapeutic opportunities

ED Mock, B Gagestein, M van der Stelt - Progress in Lipid Research, 2023 - Elsevier
Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …

Recent progress of drug nanoformulations targeting to brain

AR Khan, X Yang, M Fu, G Zhai - Journal of Controlled Release, 2018 - Elsevier
Most of the potential therapeutic agents capable to modulate the pathophysiology or treat
the neurological disorders and brain tumors are useless in the current modern and …

Photobiomodulation (blue and green light) encourages osteoblastic-differentiation of human adipose-derived stem cells: role of intracellular calcium and light-gated …

Y Wang, YY Huang, Y Wang, P Lyu, MR Hamblin - Scientific reports, 2016 - nature.com
Human adipose-derived stem cells (hASCs) have the potential to differentiate into several
different cell types including osteoblasts. Photobiomodulation (PBM) or low level laser …

Convergence of peptidergic and non‐peptidergic protein markers in the human dorsal root ganglion and spinal dorsal horn

SI Shiers, I Sankaranarayanan… - Journal of …, 2021 - Wiley Online Library
Peripheral sensory neurons are characterized by their size, molecular profiles, and
physiological responses to specific stimuli. In mouse, the peptidergic and non‐peptidergic …

TRPV1 regulates ApoE4-disrupted intracellular lipid homeostasis and decreases synaptic phagocytosis by microglia

C Wang, J Lu, X Sha, Y Qiu, H Chen, Z Yu - Experimental & molecular …, 2023 - nature.com
Although the ε4 allele of the apolipoprotein E (ApoE4) gene has been established as a
genetic risk factor for many neurodegenerative diseases, including Alzheimer's disease, the …

Multifunctional TRPV1 ion channels in physiology and pathology with focus on the brain, vasculature, and some visceral systems

MV Storozhuk, OF Moroz… - BioMed research …, 2019 - Wiley Online Library
TRPV1 has been originally cloned as the heat and capsaicin receptor implicated in acute
pain signalling, while further research has shifted the focus to its importance in chronic pain …

An integrated analysis of rare CNV and exome variation in Autism Spectrum Disorder using the Infinium PsychArray

E Bacchelli, C Cameli, M Viggiano, R Igliozzi… - Scientific Reports, 2020 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental condition with a complex and
heterogeneous genetic etiology. While a proportion of ASD risk is attributable to common …

[HTML][HTML] Oleoylethanolamide, neuroinflammation, and alcohol abuse

L Orio, F Alen, FJ Pavón, A Serrano… - Frontiers in molecular …, 2019 - frontiersin.org
Neuroinflammation is a complex process involved in the physiophatology of many central
nervous system diseases, including addiction. Alcohol abuse is characterized by induction …

The mysteries of capsaicin-sensitive afferents

MJM Fischer, CI Ciotu, A Szallasi - Frontiers in Physiology, 2020 - frontiersin.org
A fundamental subdivision of nociceptive sensory neurons is named after their unique
sensitivity to capsaicin, the pungent ingredient in hot chili peppers: these are the capsaicin …

TrpV1 receptor activation rescues neuronal function and network gamma oscillations from Aβ-induced impairment in mouse hippocampus in vitro

H Balleza-Tapia, S Crux, Y Andrade-Talavera… - Elife, 2018 - elifesciences.org
Amyloid-β peptide (Aβ) forms plaques in Alzheimer's disease (AD) and is responsible for
early cognitive deficits in AD patients. Advancing cognitive decline is accompanied by …