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[HTML][HTML] Molecular mechanisms of antibacterial multidrug resistance
MN Alekshun, SB Levy - Cell, 2007 - cell.com
Treatment of infections is compromised worldwide by the emergence of bacteria that are
resistant to multiple antibiotics. Although classically attributed to chromosomal mutations …
resistant to multiple antibiotics. Although classically attributed to chromosomal mutations …
[HTML][HTML] Community-acquired pneumonia
TM File - The Lancet, 2003 - thelancet.com
This seminar reviews important features and management issues of community-acquired
pneumonia (CAP) that are especially relevant to immunocompetent adults in light of new …
pneumonia (CAP) that are especially relevant to immunocompetent adults in light of new …
Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults
Improving the care of adult patients with community-acquired pneumonia (CAP) has been
the focus of many different organizations, and several have developed guidelines for …
the focus of many different organizations, and several have developed guidelines for …
Depletion of alveolar macrophages during influenza infection facilitates bacterial superinfections
Viruses such as influenza suppress host immune function by a variety of methods. This may
result in significant morbidity through several pathways, including facilitation of secondary …
result in significant morbidity through several pathways, including facilitation of secondary …
Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes
Bacterial pathogens evolve during the infection of their human host 1, 2, 3, 4, 5, 6, 7, 8, but
separating adaptive and neutral mutations remains challenging 9, 10, 11. Here we identify …
separating adaptive and neutral mutations remains challenging 9, 10, 11. Here we identify …
Alternating antibiotic treatments constrain evolutionary paths to multidrug resistance
Alternating antibiotic therapy, in which pairs of drugs are cycled during treatment, has been
suggested as a means to inhibit the evolution of de novo resistance while avoiding the …
suggested as a means to inhibit the evolution of de novo resistance while avoiding the …
Update of practice guidelines for the management of community-acquired pneumonia in immunocompetent adults
The Infectious Diseases Society of America (IDSA) produced guidelines for community-
acquired pneumonia (CAP) in immunocompetent adults in 1998 and again in 2000 [1, 2] …
acquired pneumonia (CAP) in immunocompetent adults in 1998 and again in 2000 [1, 2] …
Bacterial gene amplification: implications for the evolution of antibiotic resistance
Recent data suggest that, in response to the presence of antibiotics, gene duplication and
amplification (GDA) constitutes an important adaptive mechanism in bacteria. For example …
amplification (GDA) constitutes an important adaptive mechanism in bacteria. For example …
High Prevalence of Antimicrobial Resistance among Clinical Streptococcus pneumoniae Isolates in Asia (an ANSORP Study)
ABSTRACT A total of 685 clinical Streptococcus pneumoniae isolates from patients with
pneumococcal diseases were collected from 14 centers in 11 Asian countries from January …
pneumococcal diseases were collected from 14 centers in 11 Asian countries from January …
Antimicrobial treatment guidelines for acute bacterial rhinosinusitis.
Abstract Treatment guidelines developed by the Sinus and Allergy Health Partnership for
acute bacterial rhinosinusitis (ABRS) were originally published in 2000. These guidelines …
acute bacterial rhinosinusitis (ABRS) were originally published in 2000. These guidelines …