Tumor blood vessels are a key target for cancer therapeutic management. Tumor cells
secrete high levels of pro-angiogenic factors which contribute to the creation of an abnormal …

Implantable biosensors are valuable scientific tools for basic neuroscience research and
clinical applications. Neurotechnologies provide direct readouts of neurological signal and …

To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-
genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence …

Krüppel-like factors (KLFs) are a family of DNA-binding transcriptional regulators with
diverse and essential functions in a multitude of cellular processes, including proliferation …

Although the function of the autonomic nervous system (ANS) in mediating the flight-or-fight
response was recognized decades ago, the crucial role of peripheral innervation in …

Pericytes are functional components of the neurovascular unit (NVU). They provide support
to other NVU components and maintain normal physiological functions of the blood-brain …

Remarkable advances in nano delivery systems have provided new hope for tumor
prevention, diagnosis and treatment. However, only limited clinical therapeutic effects …

Dopamine (DA), a neurotransmitter in the central nervous system (CNS), has modulatory
functions at the systemic level. The peripheral and central nervous systems have …

Pituitary adenomas (PAs) are neoplasms derived from the endocrine cells of the anterior
pituitary gland. Most frequently, they are benign tumors, but may sometimes display an …

Nanomedicines including liposomes, micelles, and nanoparticles based on the enhanced
permeability and retention (EPR) effect have become the mainstream for tumor treatment …