Drug delivery systems are generally believed to comprise drugs and excipients. A peptide–
drug conjugate is a single molecule that can simultaneously play multiple roles in a drug …

Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole
ring are readily able to bind with a variety of enzymes and receptors in biological system via …

Despite many advances in the past years, the treatment of metastatic prostate cancer still
remains challenging. In recent years, prostate-specific membrane antigen (PSMA) inhibitors …

On the basis of the high and consistent expression of prostate-specific membrane antigen
(PSMA) in metastatic prostate cancer (PC), the goal of this study was the development …

The detection of prostate cancer lesions by PET imaging of the prostate-specific membrane
antigen (PSMA) has gained highest clinical impact during the last years. 68Ga-labelled Glu …

The γ-secretase complex, comprising presenilin 1 (PS1), PEN-2, APH-1 and nicastrin, is a
membrane-embedded protease that controls a number of important cellular functions …

As described in more detail in other contributions in this issue of Seminars in Nuclear
Medicine, prostate-specific membrane antigen (PSMA) has become one of the most …

In recent years, several radioligands targeting prostate-specific membrane antigen (PSMA)
have been clinically introduced as a new class of theranostic radiopharmaceuticals for the …

Since prostate-specific membrane antigen (PSMA) is up-regulated in nearly all stages of
prostate cancer (PCa), PSMA can be considered as a viable diagnostic biomarker and …

Background Due to its high expression in prostate cancer, PSMA (prostate-specific
membrane antigen) represents an ideal target for both diagnostic imaging and …