Ribosome biogenesis in plants: from functional 45S ribosomal DNA organization to ribosome assembly factors
J Sáez-Vásquez, M Delseny - The Plant Cell, 2019 - academic.oup.com
Abstract The transcription of 18S, 5.8 S, and 18S rRNA genes (45S rDNA), cotranscriptional
processing of pre-rRNA, and assembly of mature rRNA with ribosomal proteins are the …
processing of pre-rRNA, and assembly of mature rRNA with ribosomal proteins are the …
CRISPR/Cas system and factors affecting its precision and efficiency
The diverse applications of genetically modified cells and organisms require more precise
and efficient genome-editing tool such as clustered regularly interspaced short palindromic …
and efficient genome-editing tool such as clustered regularly interspaced short palindromic …
Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells
RNA-based regulation and CRISPR/Cas transcription factors (CRISPR-TFs) have the
potential to be integrated for the tunable modulation of gene networks. A major limitation of …
potential to be integrated for the tunable modulation of gene networks. A major limitation of …
RNA virus microRNA that mimics a B-cell oncomiR
MicroRNAs (miRNAs) are small RNAs that play a regulatory role in numerous and diverse
eukaryotic cellular processes. Virus-encoded miRNAs have garnered much interest …
eukaryotic cellular processes. Virus-encoded miRNAs have garnered much interest …
[HTML][HTML] Disengaging polymerase: terminating RNA polymerase II transcription in budding yeast
Termination of transcription by RNA polymerase II requires two distinct processes: The
formation of a defined 3′ end of the transcribed RNA, as well as the disengagement of RNA …
formation of a defined 3′ end of the transcribed RNA, as well as the disengagement of RNA …
Engineering synthetic gene circuits in living cells with CRISPR technology
One of the goals of synthetic biology is to build regulatory circuits that control cell behavior,
for both basic research purposes and biomedical applications. The ability to build …
for both basic research purposes and biomedical applications. The ability to build …
mTORC1 directly phosphorylates and regulates human MAF1
Abstract mTORC1 is a central regulator of growth in response to nutrient availability, but few
direct targets have been identified. RNA polymerase (pol) III produces a number of essential …
direct targets have been identified. RNA polymerase (pol) III produces a number of essential …
Mechanism of eukaryotic RNA polymerase III transcription termination
Gene expression in organisms involves many factors and is tightly controlled. Although
much is known about the initial phase of transcription by RNA polymerase III (Pol III), the …
much is known about the initial phase of transcription by RNA polymerase III (Pol III), the …
Transcription termination by the eukaryotic RNA polymerase III
RNA polymerase (pol) III transcribes a multitude of tRNA and 5S rRNA genes as well as
other small RNA genes distributed through the genome. By being sequence-specific …
other small RNA genes distributed through the genome. By being sequence-specific …
Gene-specific control of tRNA expression by RNA polymerase II
Increasing evidence suggests that tRNA levels are dynamically and specifically regulated in
response to internal and external cues to modulate the cellular translational program …
response to internal and external cues to modulate the cellular translational program …