Mitochondria control cellular fate by various mechanisms and are key drivers of cellular
metabolism. Although the main function of mitochondria is energy production, they are also …

The observation that unhealthy diets (those that are low in whole grains, fruits and
vegetables, and high in sugar, salt, saturated fat and ultra-processed foods) are a major risk …

Carnitine is a medically needful nutrient that contributes in the production of energy and the
metabolism of fatty acids. Bioavailability is higher in vegetarians than in people who eat …

Alzheimer's disease (AD) is determined by various pathophysiological mechanisms starting
10–25 years before the onset of clinical symptoms. As multiple functionally interconnected …

L-Carnitine (levocarnitine) is a naturally occurring compound found in all mammalian
species. The most important biological function of L-carnitine is in the transport of fatty acids …

ABSTRACT Background Trimethylamine N-oxide (TMAO), a compound derived from diet
and metabolism by the gut microbiome, has been associated with several chronic diseases …

Type 2 diabetes is a highly prevalent chronic metabolic disorder characterized by
hyperglycemia and associated with several complications such as retinopathy …

Modulation of endogenous cellular defense mechanisms represents an innovative approach
to therapeutic intervention in diseases causing chronic tissue damage, such as in …

l-carnitine is present in mammalian cells as free carnitine and acylcarnitines. The
acylcarnitine profile has been shown to be useful in identifying inborn errors of metabolism …

Liver and serum metabolites of obese and lean mice fed on high fat or normal diets were
analyzed using ultraperformance liquid chromatography− quadrupole-time-of-flight mass …