Potential second-hits in hereditary hemorrhagic telangiectasia
C Bernabeu, P Bayrak-Toydemir, J McDonald… - Journal of Clinical …, 2020 - mdpi.com
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant genetic disorder
that presents with telangiectases in skin and mucosae, and arteriovenous malformations …
that presents with telangiectases in skin and mucosae, and arteriovenous malformations …
Recent advances in basic research for brain arteriovenous malformation
Arteriovenous malformations (AVMs) are abnormal connections of vessels that shunt blood
directly from arteries into veins. Rupture of brain AVMs (bAVMs) can cause life-threatening …
directly from arteries into veins. Rupture of brain AVMs (bAVMs) can cause life-threatening …
Glioblastoma stem cells exploit the αvβ8 integrin-TGFβ1 signaling axis to drive tumor initiation and progression
PA Guerrero, JH Tchaicha, Z Chen, JE Morales… - Oncogene, 2017 - nature.com
Glioblastoma (GBM) is a primary brain cancer that contains populations of stem-like cancer
cells (GSCs) that home to specialized perivascular niches. GSC interactions with their niche …
cells (GSCs) that home to specialized perivascular niches. GSC interactions with their niche …
Effect of elevation of vascular endothelial growth factor level on exacerbation of hemorrhage in mouse brain arteriovenous malformation
OBJECTIVE A high level of vascular endothelial growth factor (VEGF) has been implicated
in brain arteriovenous malformation (bAVM) bleeding and rupture. However, direct evidence …
in brain arteriovenous malformation (bAVM) bleeding and rupture. However, direct evidence …
Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease
Y Cao, H Su, J Zeng, Y **e, Z Liu, F Liu, Y Qiu, F Yi… - Translational …, 2024 - Elsevier
Diabetic kidney disease (DKD) is one of the leading causes to develop end-stage kidney
disease worldwide. Pericytes are implicated in the development of tissue fibrosis. However …
disease worldwide. Pericytes are implicated in the development of tissue fibrosis. However …
Dysregulation of microRNA and intracerebral hemorrhage: roles in neuroinflammation
H Kashif, D Shah, S Sukumari-Ramesh - International journal of …, 2021 - mdpi.com
Intracerebral hemorrhage (ICH) is a major public health problem and devastating subtype of
stroke with high morbidity and mortality. Notably, there is no effective treatment for ICH …
stroke with high morbidity and mortality. Notably, there is no effective treatment for ICH …
Cellular loci involved in the development of brain arteriovenous malformations
Brain arteriovenous malformations (bAVMs) are abnormal vessels that are prone to rupture,
causing life-threatening intracranial bleeding. The mechanism of bAVM formation is poorly …
causing life-threatening intracranial bleeding. The mechanism of bAVM formation is poorly …
[HTML][HTML] miR‑222 regulates brain injury and inflammation following intracerebral hemorrhage by targeting ITGB8
YY Bai, JZ Niu - Molecular Medicine Reports, 2020 - spandidos-publications.com
Intracerebral hemorrhage (ICH) is a disease associated with high mortality and morbidity.
MicroRNAs (miRNAs) have been reported to be associated with the pathogenesis of …
MicroRNAs (miRNAs) have been reported to be associated with the pathogenesis of …
CpG-ODN exerts a neuroprotective effect via the TLR9/pAMPK signaling pathway by activation of autophagy in a neonatal HIE rat model
L Ye, Z Feng, D Doycheva, J Malaguit, B Dixon… - Experimental …, 2018 - Elsevier
Abstract Hypoxic Ischemic Encephalopathy (HIE) is an injury caused to the brain due to
prolonged lack of oxygen and blood supply which results in death or long-term disabilities …
prolonged lack of oxygen and blood supply which results in death or long-term disabilities …
Anti-inflammation conferred by stimulation of CD200R1 via Dok1 pathway in rat microglia after germinal matrix hemorrhage
Z Feng, L Ye, D Klebe, Y Ding, ZN Guo… - Journal of Cerebral …, 2019 - journals.sagepub.com
CD200 has been reported to be neuroprotective in neurodegenerative diseases. However,
the potential protective effects of CD200 in germinal matrix hemorrhage (GMH) have not …
the potential protective effects of CD200 in germinal matrix hemorrhage (GMH) have not …