In the late 19th century, postmortem examinations demonstrated a possible relationship
between thrombotic occlusion of a coronary artery and myocardial infarction (MI). 1 …

Objective To obtain summary estimates of the accuracy of a single baseline measurement of
the Elecsys Troponin T high-sensitive assay (Roche Diagnostics) for the diagnosis of acute …

In the late 19th century, post-mortem examinations demonstrated a possible relationship
between thrombotic occlusion of a coronary artery and myocardial infarction (MI). 1 …

Cardiovascular toxicity remains a major cause of concern during preclinical and clinical
development as well as contributing to post-approval withdrawal of medicines. This issue is …

It is only a matter of time before the use of high-sensitivity cardiac troponin assays (hs-cTn)
becomes common throughout the United States. In preparation for this inevitability, this …

BACKGROUND High-sensitivity cardiac troponin (hs-cTn) assays are now available that can
detect measurable troponin in significantly more individuals in the general population than …

The use of biomarkers is undisputed in the diagnosis of primary myocardial infarction (MI),
but their value for identifying MI is less well studied in the postoperative phase following …

Diabetic heart disease (DHD) is the leading cause of morbidity and mortality among the
people with diabetes, with approximately 80% of the deaths in diabetics are due to …

Importance It is currently unknown whether the uniform (universal clinical practice for more
than 2 decades) or 2 sex-specific cutoff levels are preferable when using high-sensitivity …

Background The aim of this study is to determine the 99th upper-reference limit (URL) for
cardiac troponin T (cTnT) in Italian apparently healthy subjects. Methods The reference …