Amyloid-β (Aβ) peptide is commonly found in human Alzheimer's disease (AD) brain and is
the main component of Alzheimer amyloid plaques. The predominant forms of Aβ in the …

Introduction 3. Basic aspects of adenosine as a neuromodulator relevant for cognitive
functions 4. Effects of adenosine receptor antagonists on cognitive deficits in aged rodents …

Microglia are implicated in neurodegeneration, potentially by phagocytosing neurons, but it
is unclear how to block the detrimental effects of microglia while preserving their beneficial …

Increased brain deposition of amyloid β protein (Aβ) and cognitive deficits are classical
signals of Alzheimer's disease (AD) that have been highly associated with inflammatory …

Alzheimer's disease (AD) is a progressive neurodegenerative disease and the most
common form of dementia, representing about 60–70% of cases. Curcumin is a natural …

This study is to examine if hydrogen-rich saline reduced amyloid β (Aβ) induced neural
inflammation, and learning and memory deficits in a rat model. SD male rats (n= 84, 280 …

Objective Parkinson's disease (PD) may be caused by the interaction of a number of factors,
including genetics, toxins, oxidative stress, mitochondrial abnormalities, and aging. Studies …

Object location task (OLT) has been used as a model of hippocampal-dependent memory.
Despite this application, there is neither a consistent pharmacological validation of NMDA …

In this study, the effect of Chrysin (5, 7-dihydroxyflavone), an important member of the
flavonoid family, on memory impairment, oxidative stress and BDNF reduction generated by …

Type 2 diabetes mellitus is a risk factor of Alzheimer's disease (AD), most likely linked to an
impairment of insulin signaling in the brain. Liraglutide, a novel long-lasting glucagon-like …