Summary Δ 9-tetrahydrocannabinol (THC) and its sibling, cannabidiol (CBD), are produced
by the same Cannabis plant and have similar chemical structures but differ dramatically in …

Depression is one of the leading causes of morbidity and mortality globally and in the United
States. 1 Depression affects individuals of all ages. 2 Among adolescents aged 13 to 18, the …

A major public health concern of cannabis legalization is that it may result in an increase in
psychotic disorders. We examined changes in emergency department (ED) visits for …

Objective: The United States is in the midst of rapidly changing laws regarding cannabis.
The increasing availability of cannabis for recreational and medical use requires that mental …

Smoking of cigarettes among young adolescents is a pressing public health issue. However,
the neural mechanisms underlying smoking initiation and sustenance during adolescence …

Substance use in adolescence is a known risk factor for the development of neuropsychiatric
and substance use disorders in adulthood. This is in part due to the fact that critical aspects …

Addictions are heritable and unfold dynamically across the lifespan. One prominent
neurobiological theory proposes that substance-induced changes in neural circuitry promote …

Marijuana is perceived as a harmless drug, and its recreational use has gained popularity
among young individuals. The concentration of active ingredients in recreational …

Cannabis use peaks in adolescence, and adolescents may be more vulnerable to the neural
effects of cannabis and cannabis-related harms due to ongoing brain development during …

Increased cannabis availability has contributed to increased use with concomitant incidence
of adverse effects. One risk factor for adverse drug reactions may be age. There is preclinical …