Consensuses, controversies, and future directions in treatment deintensification for human papillomavirus‐associated oropharyngeal cancer
The most common cancer caused by human papillomavirus (HPV) infection in the United
States is oropharyngeal cancer (OPC), and its incidence has been rising since the turn of the …
States is oropharyngeal cancer (OPC), and its incidence has been rising since the turn of the …
[HTML][HTML] Improving immunovirotherapies: the intersection of mathematical modelling and experiments
CE Engeland, JPW Heidbuechel, RP Araujo… - ImmunoInformatics, 2022 - Elsevier
Combined oncolytic virotherapy and immunotherapy (immunovirotherapy) protocols
represent a promising treatment strategy for a range of cancers and offer many advantages …
represent a promising treatment strategy for a range of cancers and offer many advantages …
Mathematical modeling of radiotherapy: impact of model selection on estimating minimum radiation dose for tumor control
Introduction Radiation therapy (RT) is one of the most common anticancer therapies. Yet,
current radiation oncology practice does not adapt RT dose for individual patients, despite …
current radiation oncology practice does not adapt RT dose for individual patients, despite …
A practical guide for the generation of model-based virtual clinical trials
Mathematical modeling has made significant contributions to drug design, development, and
optimization. Virtual clinical trials that integrate mathematical models to explore patient …
optimization. Virtual clinical trials that integrate mathematical models to explore patient …
Calibrating tumor growth and invasion parameters with spectral spatial analysis of cancer biopsy tissues
The reaction-diffusion equation is widely used in mathematical models of cancer. The
calibration of model parameters based on limited clinical data is critical to using reaction …
calibration of model parameters based on limited clinical data is critical to using reaction …
A novel approach to predict acute radiation dermatitis in patients with head and neck cancer using a model based on Bayesian probability
Purpose In this study, we aimed to establish a method for predicting the probability of each
acute radiation dermatitis (ARD) grade during the head and neck Volumetric Modulated Arc …
acute radiation dermatitis (ARD) grade during the head and neck Volumetric Modulated Arc …
Lessons and Opportunities for Biomarker-Driven Radiation Personalization in Head and Neck Cancer
Head and neck cancer is notoriously challenging to treat in part because it constitutes an
anatomically and biologically diverse group of cancers with heterogeneous prognoses …
anatomically and biologically diverse group of cancers with heterogeneous prognoses …
Simulating tumor volume dynamics in response to radiotherapy: Implications of model selection
From the beginning of the usage of radiotherapy (RT) for cancer treatment, mathematical
modeling has been integral to understanding radiobiology and for designing treatment …
modeling has been integral to understanding radiobiology and for designing treatment …
Harnessing Flex Point Symmetry to Estimate Logistic Tumor Population Growth
S Pasetto, I Harshe, R Brady-Nicholls… - Bulletin of Mathematical …, 2024 - Springer
The observed time evolution of a population is well approximated by a logistic growth
function in many research fields, including oncology, ecology, chemistry, demography …
function in many research fields, including oncology, ecology, chemistry, demography …
Combining mechanisms of growth arrest in solid tumours: a mathematical investigation
The processes underpinning solid tumour growth involve the interactions between various
healthy and tumour tissue components and the vasculature, and can be affected in different …
healthy and tumour tissue components and the vasculature, and can be affected in different …