PackMem: a versatile tool to compute and visualize interfacial packing defects in lipid bilayers

R Gautier, A Bacle, ML Tiberti, PF Fuchs, S Vanni… - Biophysical journal, 2018 - cell.com
The analysis of the structural organization of lipid bilayers is generally performed across the
direction normal to the bilayer/water interface, whereas the surface properties of the bilayer …

Glued in lipids: Lipointoxication in cystic fibrosis

C Vandebrouck, T Ferreira - EBioMedicine, 2020 - thelancet.com
Cystic Fibrosis (CF) is an autosomal recessive disease caused by mutations in the CF
transmembrane regulator (CFTR) gene, which encodes a chloride channel located at the …

[HTML][HTML] Modulation of cellular membrane properties as a potential therapeutic strategy to counter lipointoxication in obstructive pulmonary diseases

L Kadri, R Ferru-Clément, A Bacle, LA Payet… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Maintaining the equilibrium between saturated and unsaturated fatty acids within membrane
phospholipids (PLs) is crucial to sustain the optimal membrane biophysical properties …

A small molecule screen for paqr-2 suppressors identifies Tyloxapol as a membrane fluidizer for C. elegans and mammalian cells

M Ruiz, E Svensk, E Einarsson, EP Grahn… - Biochimica et Biophysica …, 2022 - Elsevier
Defects in cell membrane homeostasis are implicated in numerous disorders, including
cancer, neurodegeneration and diabetes. There is therefore a need for a powerful model to …

[PDF][PDF] BBA-Molecular Basis of Disease

L Kadri, R Ferru-Clément, A Bacle, LA Payet… - researchgate.net
Maintaining the equilibrium between saturated and unsaturated fatty acids within membrane
phospholipids (PLs) is crucial to sustain the optimal membrane biophysical properties …

[PDF][PDF] Etude in silico des gouttelettes lipidiques et de leur interaction avec des protéines périphériques via des hélices amphipathiques

A Bacle - 2016 - theses.fr
Tout d'abord, je remercie mon directeur de thèse Patrick Fuchs pour tout ce qu'il a pu
m'apporter lors de ces 4 dernières années. Il a été un enseignant, un manager et un mentor …