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Noise-induced hearing loss
N Natarajan, S Batts, KM Stankovic - Journal of clinical medicine, 2023 - mdpi.com
Noise-induced hearing loss (NIHL) is the second most common cause of sensorineural
hearing loss, after age-related hearing loss, and affects approximately 5% of the world's …
hearing loss, after age-related hearing loss, and affects approximately 5% of the world's …
Neuronal connectivity and interactions between the auditory and limbic systems. Effects of noise and tinnitus
KS Kraus, B Canlon - Hearing research, 2012 - Elsevier
Acoustic experience such as sound, noise, or absence of sound induces structural or
functional changes in the central auditory system but can also affect limbic regions such as …
functional changes in the central auditory system but can also affect limbic regions such as …
Emerging treatments for noise-induced hearing loss
N Oishi, J Schacht - Expert opinion on emerging drugs, 2011 - Taylor & Francis
Introduction: Approximately 5% of the population worldwide suffers from industrial, military or
recreational noise-induced hearing loss (NIHL) at a great economic cost and detriment to …
recreational noise-induced hearing loss (NIHL) at a great economic cost and detriment to …
Toward cochlear therapies
J Wang, JL Puel - Physiological reviews, 2018 - journals.physiology.org
Sensorineural hearing impairment is the most common sensory disorder and a major health
and socio-economic issue in industrialized countries. It is primarily due to the degeneration …
and socio-economic issue in industrialized countries. It is primarily due to the degeneration …
NF-κB functions in the nervous system: from development to disease
S Mémet - Biochemical pharmacology, 2006 - Elsevier
The transcription factor nuclear factor-κB (NF-κB) is an ubiquitously expressed dimeric
molecule with post-translationally regulated activity. Its role in the immune system and host …
molecule with post-translationally regulated activity. Its role in the immune system and host …
Noise‐induced hearing loss: updates on molecular targets and potential interventions
H Mao, Y Chen - Neural Plasticity, 2021 - Wiley Online Library
Noise overexposure leads to hair cell loss, synaptic ribbon reduction, and auditory nerve
deterioration, resulting in transient or permanent hearing loss depending on the exposure …
deterioration, resulting in transient or permanent hearing loss depending on the exposure …
Estrogen receptor β protects against acoustic trauma in mice
I Meltser, Y Tahera, E Simpson, M Hultcrantz… - The Journal of clinical …, 2008 - jci.org
The hormone estradiol affects the auditory system both by itself and by its interaction with
neuroprotective factors. In this study, we examined the role of estrogen receptors (ERs) in …
neuroprotective factors. In this study, we examined the role of estrogen receptors (ERs) in …
Molecular regulation of auditory hair cell death and approaches to protect sensory receptor cells and/or stimulate repair following acoustic trauma
CT Dinh, S Goncalves, E Bas… - Frontiers in Cellular …, 2015 - frontiersin.org
Loss of auditory sensory hair cells (HCs) is the most common cause of hearing loss. This
review addresses the signaling pathways that are involved in the programmed and necrotic …
review addresses the signaling pathways that are involved in the programmed and necrotic …
The injured cochlea as a target for inflammatory processes, initiation of cell death pathways and application of related otoprotective strategies
R N. Abi-Hachem, A Zine… - Recent patents on CNS …, 2010 - benthamdirect.com
One of the causes of sensorineural hearing loss is the loss of auditory hair cells following
exposure to environmental stresses. Auditory hair cell death in response to cochlear trauma …
exposure to environmental stresses. Auditory hair cell death in response to cochlear trauma …
Dexamethasone protects auditory hair cells against TNFα-initiated apoptosis via activation of PI3K/Akt and NFκB signaling
BACKGROUND: Tumor necrosis factor alpha (TNFα) is associated with trauma-induced
hearing loss. Local treatment of cochleae of trauma-exposed animals with a glucocorticoid is …
hearing loss. Local treatment of cochleae of trauma-exposed animals with a glucocorticoid is …