The emergence of collagen I in vertebrates resulted in a dramatic increase in the stiffness of
the extracellular environment, supporting long-range force propagation and the …

Cell migration is a vital and dynamic process required for the development of multicellular
organisms and for immune system responses, tissue renewal and wound healing in adults. It …

Epidermolysis bullosa simplex (EBS) is a group of inherited keratinopathies that, in most
cases, arise due to mutations in keratins and lead to intraepidermal ruptures. The cellular …

Keratin intermediate filament (IF) proteins constitute the major cytoskeletal components in
epithelial cells. Missense mutations in keratin 5 (K5; also known as KRT5) or keratin 14 …

Keratins make up a major portion of epithelial intermediate filament proteins. The widely
diverse keratins are found in both the small and large intestines. The human intestine mainly …

14-3-3s are a family of structurally similar proteins that bind to phosphoserine or
phosphothreonine residues, forming the central signaling hub that coordinates or integrates …

The stress-induced keratin intermediate filament gene/protein KRT16 (K16) is spatially
restricted to the suprabasal compartment of the epidermis and extensively used as a …

Abstract The Apoptosis Stimulating Protein of p53 2 (ASPP2) is a heterozygous insufficient
tumor suppressor; however, its molecular mechanism (s) in tumor suppression is not …

In malignant airway epithelial cells, structural abnormalities were evident from the
cytokeratin organization. To determine whether the cytokeratins themselves were …

ABSTRACT Corneal Epithelial Stem Cells (CESCs) and their proliferative progeny, the
Transit Amplifying Cells (TACs), are responsible for homeostasis and maintaining corneal …