Changes in monocyte subsets in volunteers who received an oral wild-type Salmonella Typhi challenge and reached typhoid diagnosis criteria

FR Toapanta, J Hu, KA Shirey, PJ Bernal… - Frontiers in …, 2024 - frontiersin.org
An oral Controlled Human Infection Model (CHIM) with wild-type S. Typhi was re-established
allowing us to explore the development of immunity. In this model,~ 55% of volunteers who …

Epigenetic regulation in epithelial cells and innate lymphocyte responses to S. Typhi infection: insights into IFN-γ production and intestinal immunity

R Salerno-Goncalves, H Chen, AC Bafford… - Frontiers in …, 2024 - frontiersin.org
Infection by Salmonella enterica serovar Typhi (S. Typhi), the cause of enteric fevers, is low
in high-income countries but persistent in low-and middle-income countries, resulting in …

毒力因子 SpvD 在调控 NF-κB 通路致肠炎沙门菌 感染中的作用机制研究.

许增权, 陈家良, 侯悦, 庄吉… - Journal of Food Safety …, 2024 - search.ebscohost.com
目的探讨毒力因子SpvD 在调控NF-κB 通路致肠炎沙门菌感染中的作用机制. 方法将肠炎沙门菌
PLAGH-086 野生株, spvD 基因缺失株和回补株作为研究对象, 进行Raw 264.7 细胞和C57BL/6 …