Raman spectroscopy for chemical biology research

K Dodo, K Fujita, M Sodeoka - Journal of the American Chemical …, 2022‏ - ACS Publications
In chemical biology research, various fluorescent probes have been developed and used to
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …

Label-free microfluidic cell sorting and detection for rapid blood analysis

N Lu, HM Tay, C Petchakup, L He, L Gong, KK Maw… - Lab on a Chip, 2023‏ - pubs.rsc.org
Blood tests are considered as standard clinical procedures to screen for markers of diseases
and health conditions. However, the complex cellular background (> 99.9% RBCs) and …

Biological imaging of chemical bonds by stimulated Raman scattering microscopy

F Hu, L Shi, W Min - Nature methods, 2019‏ - nature.com
All molecules consist of chemical bonds, and much can be learned from map** the
spatiotemporal dynamics of these bonds. Since its invention a decade ago, stimulated …

Machine learning for microfluidic design and control

D McIntyre, A Lashkaripour, P Fordyce, D Densmore - Lab on a Chip, 2022‏ - pubs.rsc.org
Microfluidics has developed into a mature field with applications across science and
engineering, having particular commercial success in molecular diagnostics, next …

Raman microspectroscopy for microbiology

KS Lee, Z Landry, FC Pereira, M Wagner… - Nature Reviews …, 2021‏ - nature.com
Raman microspectroscopy offers microbiologists a rapid and non-destructive technique to
assess the chemical composition of individual live microorganisms in near real time. In this …

Multi-molecular hyperspectral PRM-SRS microscopy

W Zhang, Y Li, AA Fung, Z Li, H Jang, H Zha… - Nature …, 2024‏ - nature.com
Lipids play crucial roles in many biological processes. Map** spatial distributions and
examining the metabolic dynamics of different lipid subtypes in cells and tissues are critical …

Raman image-activated cell sorting

N Nitta, T Iino, A Isozaki, M Yamagishi… - Nature …, 2020‏ - nature.com
The advent of image-activated cell sorting and imaging-based cell picking has advanced our
knowledge and exploitation of biological systems in the last decade. Unfortunately, they …

Trends in digital image processing of isolated microalgae by incorporating classification algorithm

JWR Chong, KS Khoo, KW Chew, HY Ting… - Biotechnology …, 2023‏ - Elsevier
Identification of microalgae species is of importance due to the uprising of harmful algae
blooms affecting both the aquatic habitat and human health. Despite this occurence …

High-throughput Raman flow cytometry and beyond

J Gala de Pablo, M Lindley, K Hiramatsu… - Accounts of Chemical …, 2021‏ - ACS Publications
Conspectus Flow cytometry is a powerful tool with applications in diverse fields such as
microbiology, immunology, virology, cancer biology, stem cell biology, and metabolic …

AI on a chip

A Isozaki, J Harmon, Y Zhou, S Li, Y Nakagawa… - Lab on a Chip, 2020‏ - pubs.rsc.org
Artificial intelligence (AI) has dramatically changed the landscape of science, industry,
defence, and medicine in the last several years. Supported by considerably enhanced …