Pichia pastoris: A highly successful expression system for optimal synthesis of heterologous proteins
One of the most important branches of genetic engineering is the expression of recombinant
proteins using biological expression systems. Nowadays, different expression systems are …
proteins using biological expression systems. Nowadays, different expression systems are …
EV71 vaccine, a new tool to control outbreaks of hand, foot and mouth disease (HFMD)
Q Mao, Y Wang, L Bian, M Xu, Z Liang - Expert review of vaccines, 2016 - Taylor & Francis
ABSTRACT On December 3rd 2015, the China Food and Drug Administration (CFDA)
approved the first inactivated Enterovirus 71 (EV71) whole virus vaccine for preventing …
approved the first inactivated Enterovirus 71 (EV71) whole virus vaccine for preventing …
A self-amplifying RNA vaccine prevents enterovirus D68 infection and disease in preclinical models
NL Warner, J Archer, S Park, G Singh… - Science translational …, 2024 - science.org
The recent emergence and rapid response to severe acute respiratory syndrome
coronavirus 2 was enabled by prototype pathogen and vaccine platform approaches, driven …
coronavirus 2 was enabled by prototype pathogen and vaccine platform approaches, driven …
Yeast-based vaccines: New perspective in vaccine development and application
R Kumar, P Kumar - FEMS yeast Research, 2019 - academic.oup.com
In presently licensed vaccines, killed or attenuated organisms act as a source of
immunogens except for peptide-based vaccines. These conventional vaccines required a …
immunogens except for peptide-based vaccines. These conventional vaccines required a …
Enterovirus A71 vaccines
Enterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease
(HFMD) and herpangina. Moreover, EV-A71 infection can lead to neurological complications …
(HFMD) and herpangina. Moreover, EV-A71 infection can lead to neurological complications …
Antivirals and vaccines for Enterovirus A71
JY Lin, YA Kung, SR Shih - Journal of biomedical science, 2019 - Springer
Abstract Enterovirus A71 (EV-A71) is an important emerging virus posing a threat to children
under five years old. EV-A71 infection in infants or young children can cause hand-foot-and …
under five years old. EV-A71 infection in infants or young children can cause hand-foot-and …
Yeast-based virus-like particles as an emerging platform for vaccine development and delivery
Virus-like particles (VLPs) are empty, nanoscale structures morphologically resembling
viruses. Internal cavity, noninfectious, and particulate nature with a high density of repeating …
viruses. Internal cavity, noninfectious, and particulate nature with a high density of repeating …
Recent advances in the production of recombinant subunit vaccines in Pichia pastoris
M Wang, S Jiang, Y Wang - Bioengineered, 2016 - Taylor & Francis
Recombinant protein subunit vaccines are formulated using defined protein antigens that
can be produced in heterologous expression systems. The methylotrophic yeast Pichia …
can be produced in heterologous expression systems. The methylotrophic yeast Pichia …
Pichia pastoris (Komagataella phaffii) as a Cost-Effective Tool for Vaccine Production for Low- and Middle-Income Countries (LMICs)
S de Sá Magalhães, E Keshavarz-Moore - Bioengineering, 2021 - mdpi.com
Vaccination is of paramount importance to global health. With the advent of the more recent
pandemics, the urgency to expand the range has become even more evident. However, the …
pandemics, the urgency to expand the range has become even more evident. However, the …
HBV vaccines: advances and development
Hepatitis B virus (HBV) infection is a global public health problem that is closely related to
liver cirrhosis and hepatocellular carcinoma (HCC). The prevalence of acute and chronic …
liver cirrhosis and hepatocellular carcinoma (HCC). The prevalence of acute and chronic …