Isobaric labeling-based relative quantification in shotgun proteomics
Mass spectrometry plays a key role in relative quantitative comparisons of proteins in order
to understand their functional role in biological systems upon perturbation. In this review, we …
to understand their functional role in biological systems upon perturbation. In this review, we …
Multi-dimensional liquid chromatography in proteomics—a review
Proteomics is the large-scale study of proteins, particularly their expression, structures and
functions. This still-emerging combination of technologies aims to describe and characterize …
functions. This still-emerging combination of technologies aims to describe and characterize …
Simultaneous analysis of relative protein expression levels across multiple samples using iTRAQ isobaric tags with 2D nano LC–MS/MS
In this paper, we describe the use of iTRAQ (isobaric Tags for Relative and Absolute
Quantitation) tags for comparison of protein expression levels between multiple samples …
Quantitation) tags for comparison of protein expression levels between multiple samples …
RNA editing of Filamin A pre‐mRNA regulates vascular contraction and diastolic blood pressure
Epitranscriptomic events such as adenosine‐to‐inosine (A‐to‐I) RNA editing by ADAR can
recode mRNA s to translate novel proteins. Editing of the mRNA that encodes actin …
recode mRNA s to translate novel proteins. Editing of the mRNA that encodes actin …
Breast cancer classification based on proteotypes obtained by SWATH mass spectrometry
Accurate classification of breast tumors is vital for patient management decisions and
enables more precise cancer treatment. Here, we present a quantitative proteoty** …
enables more precise cancer treatment. Here, we present a quantitative proteoty** …
A Model of Aerobic and Anaerobic Metabolism of Hydrogen in the Extremophile Acidithiobacillus ferrooxidans
Hydrogen can serve as an electron donor for chemolithotrophic acidophiles, especially in
the deep terrestrial subsurface and geothermal ecosystems. Nevertheless, the current …
the deep terrestrial subsurface and geothermal ecosystems. Nevertheless, the current …
Desmocollin-1 is associated with pro-metastatic phenotype of luminal A breast cancer cells and is modulated by parthenolide
P Lapcik, P Sulc, L Janacova, K Jilkova… - Cellular & Molecular …, 2023 - Springer
Abstract Background Desmocollin-1 (DSC1) is a desmosomal transmembrane glycoprotein
that maintains cell-to-cell adhesion. DSC1 was previously associated with lymph node …
that maintains cell-to-cell adhesion. DSC1 was previously associated with lymph node …
Discovery and identification of serum potential biomarkers for pulmonary tuberculosis using iTRAQ‐coupled two‐dimensional LC‐MS/MS
Pulmonary tuberculosis (TB) caused by Mycobacterium tuberculosis is a chronic disease.
Currently, there are no sufficiently validated biomarkers for early diagnosis of TB infection. In …
Currently, there are no sufficiently validated biomarkers for early diagnosis of TB infection. In …
Combined proteomics and transcriptomics identifies carboxypeptidase B1 and nuclear factor κB (NF-κB) associated proteins as putative biomarkers of metastasis in …
Current prognostic factors are insufficient for precise risk-discrimination in breast cancer
patients with low grade breast tumors, which, in disagreement with theoretical prognosis …
patients with low grade breast tumors, which, in disagreement with theoretical prognosis …
Multidimensional chromatography coupled to mass spectrometry in analysing complex proteomics samples
P Horvatovich, B Hoekman… - Journal of separation …, 2010 - Wiley Online Library
Multidimensional chromatography coupled to mass spectrometry (LCn‐MS) provides more
separation power and an extended measured dynamic concentration range to analyse …
separation power and an extended measured dynamic concentration range to analyse …