Fibromyalgia: pathogenesis, mechanisms, diagnosis and treatment options update

R Siracusa, RD Paola, S Cuzzocrea… - International journal of …, 2021 - mdpi.com
Fibromyalgia is a syndrome characterized by chronic and widespread musculoskeletal pain,
often accompanied by other symptoms, such as fatigue, intestinal disorders and alterations …

Neurobiology of fibromyalgia and chronic widespread pain

KA Sluka, DJ Clauw - Neuroscience, 2016 - Elsevier
Fibromyalgia is the current term for chronic widespread musculoskeletal pain for which no
alternative cause can be identified. The underlying mechanisms, in both human and animal …

Fibromyalgia: a critical and comprehensive review

AT Borchers, ME Gershwin - Clinical reviews in allergy & immunology, 2015 - Springer
Fibromyalgia is a disorder that is part of a spectrum of syndromes that lack precise
classification. It is often considered as part of the global overview of functional somatic …

Can work make you sick? A meta-analysis of the relationships between job stressors and physical symptoms

AE Nixon, JJ Mazzola, J Bauer, JR Krueger… - Work & …, 2011 - Taylor & Francis
A meta-analysis of 79 studies reporting cross-sectional and longitudinal relationships
between physical symptoms and various occupational stressors was conducted. Stressors …

Physiology and neurobiology of stress and adaptation: central role of the brain

BS McEwen - Physiological reviews, 2007 - journals.physiology.org
The brain is the key organ of the response to stress because it determines what is
threatening and, therefore, potentially stressful, as well as the physiological and behavioral …

Common brain mechanisms of chronic pain and addiction

I Elman, D Borsook - Neuron, 2016 - cell.com
While chronic pain is considered by some to be a CNS disease, little is understood about
underlying neurobiological mechanisms. Addiction models have heuristic value in this …

[HTML][HTML] Fibromyalgia: A Review of the Pathophysiological Mechanisms and Multidisciplinary Treatment Strategies

LN Jurado-Priego, C Cueto-Ureña… - Biomedicines, 2024 - mdpi.com
Fibromyalgia is a syndrome characterized by chronic widespread musculoskeletal pain,
which may or may not be associated with muscle or joint stiffness, accompanied by other …

Mast cells, neuroinflammation and pain in fibromyalgia syndrome

TC Theoharides, I Tsilioni, M Bawazeer - Frontiers in cellular …, 2019 - frontiersin.org
Fibromyalgia Syndrome (FMS) is a disorder of chronic, generalized muscular pain,
accompanied by sleep disturbances, fatigue and cognitive dysfunction. There is no definitive …

[HTML][HTML] Reward deficiency and anti-reward in pain chronification

D Borsook, C Linnman, V Faria, AM Strassman… - Neuroscience & …, 2016 - Elsevier
Converging lines of evidence suggest that the pathophysiology of pain is mediated to a
substantial degree via allostatic neuroadaptations in reward-and stress-related brain …

Fibromyalgia: an overview

DJ Clauw - The American journal of medicine, 2009 - Elsevier
Fibromyalgia is the diagnosis given to individuals with chronic widespread musculoskeletal
pain for which no alternative cause, such as tissue inflammation or damage, can be …