Gut-liver axis: Pathophysiological concepts and clinical implications

H Tilg, TE Adolph, M Trauner - Cell Metabolism, 2022 - cell.com
Bidirectional crosstalk along the gut-liver axis controls gastrointestinal health and disease
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …

Western diets and chronic diseases

TE Adolph, H Tilg - Nature medicine, 2024 - nature.com
Abstract 'Westernization', which incorporates industrial, cultural and dietary trends, has
paralleled the rise of noncommunicable diseases across the globe. Today, the Western-style …

Gut microbiota Turicibacter strains differentially modify bile acids and host lipids

JB Lynch, EL Gonzalez, K Choy, KF Faull… - Nature …, 2023 - nature.com
Bacteria from the Turicibacter genus are prominent members of the mammalian gut
microbiota and correlate with alterations in dietary fat and body weight, but the specific …

Assessment of global health risk of antibiotic resistance genes

Z Zhang, Q Zhang, T Wang, N Xu, T Lu, W Hong… - Nature …, 2022 - nature.com
Antibiotic resistance genes (ARGs) have accelerated microbial threats to human health in
the last decade. Many genes can confer resistance, but evaluating the relative health risks of …

Methanogenic archaea in the human gastrointestinal tract

C Hoegenauer, HF Hammer, A Mahnert… - Nature Reviews …, 2022 - nature.com
The human microbiome is strongly interwoven with human health and disease. Besides
bacteria, viruses and eukaryotes, numerous archaea are located in the human …

Codiversification of gut microbiota with humans

TA Suzuki, JL Fitzstevens, VT Schmidt, H Enav… - Science, 2022 - science.org
The gut microbiomes of human populations worldwide have many core microbial species in
common. However, within a species, some strains can show remarkable population …

[HTML][HTML] Ultra-deep sequencing of Hadza hunter-gatherers recovers vanishing gut microbes

MM Carter, MR Olm, BD Merrill, D Dahan, S Tripathi… - Cell, 2023 - cell.com
The gut microbiome modulates immune and metabolic health. Human microbiome data are
biased toward industrialized populations, limiting our understanding of non-industrialized …

Intestinal Blastocystis is linked to healthier diets and more favorable cardiometabolic outcomes in 56,989 individuals from 32 countries

E Piperni, LH Nguyen, P Manghi, H Kim, E Pasolli… - Cell, 2024 - cell.com
Diet impacts human health, influencing body adiposity and the risk of develo**
cardiometabolic diseases. The gut microbiome is a key player in the diet-health axis, but …

Diet fuelling inflammatory bowel diseases: preclinical and clinical concepts

TE Adolph, J Zhang - Gut, 2022 - gut.bmj.com
The diet and gut microbiota have been extensively interrogated as a fuel for gut
inflammation in inflammatory bowel diseases (IBDs) in the last few years. Here, we review …

Cryptic diversity of cellulose-degrading gut bacteria in industrialized humans

S Moraïs, S Winkler, A Zorea, L Levin, FSP Nagies… - Science, 2024 - science.org
Humans, like all mammals, depend on the gut microbiome for digestion of cellulose, the
main component of plant fiber. However, evidence for cellulose fermentation in the human …