NIA‐AA research framework: toward a biological definition of Alzheimer's disease
CR Jack Jr, DA Bennett, K Blennow… - Alzheimer's & …, 2018 - Wiley Online Library
Abstract In 2011, the National Institute on Aging and Alzheimer's Association created
separate diagnostic recommendations for the preclinical, mild cognitive impairment, and …
separate diagnostic recommendations for the preclinical, mild cognitive impairment, and …
Religious orders study and rush memory and aging project
Background: The Religious Orders Study and Rush Memory and Aging Project are both
ongoing longitudinal clinical-pathologic cohort studies of aging and Alzheimer's disease …
ongoing longitudinal clinical-pathologic cohort studies of aging and Alzheimer's disease …
Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup
CR Jack Jr, JS Andrews, TG Beach… - Alzheimer's & …, 2024 - Wiley Online Library
Abstract The National Institute on Aging and the Alzheimer's Association convened three
separate work groups in 2011 and single work groups in 2012 and 2018 to create …
separate work groups in 2011 and single work groups in 2012 and 2018 to create …
OASIS-3: longitudinal neuroimaging, clinical, and cognitive dataset for normal aging and Alzheimer disease
ABSTRACT OASIS-3 is a compilation of MRI and PET imaging and related clinical data for
1098 participants who were collected across several ongoing studies in the Washington …
1098 participants who were collected across several ongoing studies in the Washington …
Association of amyloid and tau with cognition in preclinical Alzheimer disease: a longitudinal study
Importance Positron emission tomography (PET) imaging now allows in vivo visualization of
both neuropathologic hallmarks of Alzheimer disease (AD): amyloid-β (Aβ) plaques and tau …
both neuropathologic hallmarks of Alzheimer disease (AD): amyloid-β (Aβ) plaques and tau …
Plasma biomarker strategy for selecting patients with Alzheimer disease for antiamyloid immunotherapies
Importance Antiamyloid immunotherapies against Alzheimer disease (AD) are emerging.
Scalable, cost-effective tools will be needed to identify amyloid β (Aβ)–positive patients …
Scalable, cost-effective tools will be needed to identify amyloid β (Aβ)–positive patients …
Dementia in Down syndrome: unique insights for Alzheimer disease research
IT Lott, E Head - Nature Reviews Neurology, 2019 - nature.com
Virtually all adults with Down syndrome (DS) show the neuropathological changes of
Alzheimer disease (AD) by the age of 40 years. This association is partially due to …
Alzheimer disease (AD) by the age of 40 years. This association is partially due to …
Imaging tau and amyloid-β proteinopathies in Alzheimer disease and other conditions
Most neurodegenerative disorders are associated with aggregated protein deposits. In the
case of Alzheimer disease (AD), extracellular amyloid-β (Aβ) aggregates and intracellular …
case of Alzheimer disease (AD), extracellular amyloid-β (Aβ) aggregates and intracellular …
Tau and Aβ imaging, CSF measures, and cognition in Alzheimer's disease
Alzheimer's disease (AD) is characterized by two molecular pathologies: cerebral β-
amyloidosis in the form of β-amyloid (Aβ) plaques and tauopathy in the form of neurofibrillary …
amyloidosis in the form of β-amyloid (Aβ) plaques and tauopathy in the form of neurofibrillary …
Brain iron is associated with accelerated cognitive decline in people with Alzheimer pathology
S Ayton, Y Wang, I Diouf, JA Schneider… - Molecular …, 2020 - nature.com
Cortical iron has been shown to be elevated in Alzheimer's disease (AD), but the impact of
the directly measured iron on the clinical syndrome has not been assessed. We investigated …
the directly measured iron on the clinical syndrome has not been assessed. We investigated …