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Thermoresponsive interfaces obtained using poly (N-isopropylacrylamide)-based copolymer for bioseparation and tissue engineering applications
K Nagase - Advances in Colloid and Interface Science, 2021 - Elsevier
Abstract Poly (N-isopropylacrylamide)(PNIPAAm) is the most well-known and widely used
stimuli-responsive polymer in the biomedical field owing to its ability to undergo temperature …
stimuli-responsive polymer in the biomedical field owing to its ability to undergo temperature …
[HTML][HTML] Progress in ATRP-derived materials for biomedical applications
The continuing wave of technological breakthroughs and advances is critical for engineering
well-defined materials, particularly biomaterials, with tailored microstructure and properties …
well-defined materials, particularly biomaterials, with tailored microstructure and properties …
Poly(N-isopropylacrylamide)-based temperature- and pH-responsive polymer materials for application in biomedical fields
Y Hiruta - Polymer Journal, 2022 - nature.com
The synthesis and application of stimuli-responsive polymer materials have been
extensively studied. Among stimuli-responsive polymers, thermoresponsive poly (N …
extensively studied. Among stimuli-responsive polymers, thermoresponsive poly (N …
[HTML][HTML] Thermoresponsive block-copolymer brush-modified interfaces for effective fabrication of hepatocyte sheets
K Nagase, M Nagaoka, J Matsuda, N Kojima - Materials & Design, 2024 - Elsevier
Hepatic tissue engineering has been investigated for the treatment of liver disease. One
promising tissue is the hepatocyte sheet, cultured in temperature-responsive cell culture …
promising tissue is the hepatocyte sheet, cultured in temperature-responsive cell culture …
[HTML][HTML] bFGF-releasing biodegradable nanoparticles for effectively engrafting transplanted hepatocyte sheet
K Nagase, M Nagaoka, Y Nakano, R Utoh - Journal of Controlled Release, 2024 - Elsevier
Hepatic tissue engineering has been applied for the treatment of intractable liver diseases,
and hepatocyte sheets are promising for this purpose. However, hepatocyte sheets have …
and hepatocyte sheets are promising for this purpose. However, hepatocyte sheets have …
Brush-like polymers: design, synthesis and applications
L Yin, L Liu, N Zhang - Chemical Communications, 2021 - pubs.rsc.org
With the development of controlled polymerisation, almost all polymerisation strategies have
been successfully transplanted to surface-initiated polymerisation. The resulting polymer …
been successfully transplanted to surface-initiated polymerisation. The resulting polymer …
Thermoresponsive mixed polymer brush to effectively control the adhesion and separation of stem cells by altering temperature
K Nagase, H Wakayama, J Matsuda, N Kojima… - Materials Today Bio, 2023 - Elsevier
During the last few decades, thermoresponsive materials for modulating cell adhesion have
been investigated for the application of tissue engineering. In this study, we developed …
been investigated for the application of tissue engineering. In this study, we developed …
Umbilical cord-derived mesenchymal stem cell sheets transplanted subcutaneously enhance cell retention and survival more than dissociated stem cell injections
M Nakao, M Matsui, K Kim, N Nishiyama… - Stem Cell Research & …, 2023 - Springer
Background Human umbilical cord-derived mesenchymal stem cell (hUC-MSC) sheets have
recently attracted attention as an alternative approach to injected cell suspensions for stem …
recently attracted attention as an alternative approach to injected cell suspensions for stem …
[HTML][HTML] Thermoresponsive bio-affinity interfaces for temperature-modulated selective capture and release of targeted exosomes
The existing methods for exosome isolation, such as ultracentrifugation, size exclusion, and
affinity separation, suffer from some limitations. Herein, we aimed to develop temperature …
affinity separation, suffer from some limitations. Herein, we aimed to develop temperature …
Hydration and dehydration behaviors of poly (N-isopropylacrylamide)-grafted silica beads
K Nagase, J Matsuda, A Takeuchi, Y Ikemoto - Surfaces and Interfaces, 2023 - Elsevier
The use of poly (N-isopropyl acrylamide)(PNIPAAm) in thermoresponsive interfaces for
biomedical applications has been extensively investigated. Understanding the hydration …
biomedical applications has been extensively investigated. Understanding the hydration …