Association between diabetes mellitus/hyperglycaemia and peri‐implant diseases: systematic review and meta‐analysis

A Monje, A Catena… - Journal of clinical …, 2017 - Wiley Online Library
Aim This systematic review investigates whether hyperglycaemia/diabetes mellitus is
associated with peri‐implant diseases (peri‐implant mucositis and peri‐implantitis) …

A review of the evidence for pathogenic mechanisms that may link periodontitis and diabetes

JJ Taylor, PM Preshaw, E Lalla - Journal of clinical …, 2013 - Wiley Online Library
Aims To review the evidence for the molecular and cellular processes that may potentially
link periodontal disease and diabetes. The pathogenic roles of cytokines and metabolic …

Novel insight into the mechanisms of the bidirectional relationship between diabetes and periodontitis

F Barutta, S Bellini, M Durazzo, G Gruden - Biomedicines, 2022 - mdpi.com
Periodontitis and diabetes are two major global health problems despite their prevalence
being significantly underreported and underestimated. Both epidemiological and …

[HTML][HTML] The bidirectional association between diabetes and periodontitis, from basic to clinical

T Shinjo, F Nishimura - Japanese Dental Science Review, 2024 - Elsevier
The prevalence and severity of periodontitis are increased and advanced in diabetes.
Severe periodontitis elicits adverse effects on diabetes by impairing insulin actions due to …

Peri‐implant conditions and levels of advanced glycation end products among patients with different glycemic control

ZH Al‐Sowygh, SMA Ghani, K Sergis… - … implant dentistry and …, 2018 - Wiley Online Library
Background A close relationship between poor glycemic control and peri‐implant break
down has been demonstrated. It is hypothesized that levels of advanced glycation end …

Platelet‐rich fibrin with 1% metformin for the treatment of intrabony defects in chronic periodontitis: a randomized controlled clinical trial

AR Pradeep, K Nagpal, S Karvekar… - Journal of …, 2015 - Wiley Online Library
Background: Platelet‐rich fibrin (PRF) is a second‐generation platelet concentrate that
releases various growth factors that promote tissue regeneration. Metformin (MF), a member …

Levels of advanced glycation end products in gingival crevicular fluid of chronic periodontitis patients with and without type‐2 diabetes mellitus

Z Akram, F Alqahtani, M Alqahtani… - Journal of …, 2020 - Wiley Online Library
Background It is hypothesized that levels of advanced glycation end products (AGEs) are
higher in the gingival crevicular fluid (GCF) of chronic periodontitis (CP) patients with type‐2 …

Regenerative and protective effects of dMSC-sEVs on high-glucose-induced senescent fibroblasts by suppressing RAGE pathway and activating Smad pathway

X Bian, B Li, J Yang, K Ma, M Sun, C Zhang… - Stem cell research & …, 2020 - Springer
Background Fibroblasts are crucial for supporting normal wound healing. However, the
functional state of these cells is impaired in diabetics because of a high-glucose (HG) …

Local inflammatory reactions in patients with diabetes and periodontitis

SK Sonnenschein, J Meyle - Periodontology 2000, 2015 - Wiley Online Library
The impact of diabetes mellitus on the prevalence, severity and progression of periodontal
disease has been known for many years and intense efforts have been made to elucidate …

Pathogenic molecular mechanisms in periodontitis and peri-implantitis: role of advanced glycation end products

G Plemmenos, C Piperi - Life, 2022 - mdpi.com
Advanced Glycation End Products (AGEs), the products of the non-enzymatic oxidation of
proteins, nucleic acids, and lipids, are accumulated in periodontal tissues under …