Platinum-based drugs have maintained their preeminent position in cancer treatment
regimens even four decades after the approval of cisplatin. Although these agents have …

The concept of multi-action octahedral platinum (IV) complexes is based on the rational
derivatization of anticancer square-planar platinum (II) compounds (eg, cisplatin or …

In the last decades, inflammation has been recognized as being closely connected to
cancer, and joint strategies encompassing chemotherapeutic and anti-inflammatory agents …

Despite the enormous importance of cisplatin as a chemotherapeutic agent, its application is
impacted by dose-limiting side effects and lack of selectivity for cancer cells. Researchers …

In this work, biologically active α-lipoic acid (ALA) and its isologous 1, 2-diselenolane (SeA)
and cyclopentyl (CpA) analogues were investigated for their differences in redox potentials …

This review discusses the relationship between inflammation and cancer initiation and
progression, which has prompted research into anti-inflammatory approaches for cancer …

Betulin and α-lipoic acid are naturally occurring substances with different biological
properties. Combining two phytochemical units into a conjugate is a frequently used method …

A brand-new enhanced starvation is put forward to trigger sensitized chemotherapy:
blocking tumor-relation blood vessel formation and accelerating nutrient degradation and …

Colorectal cancer (CRC) is the fourth most common cancer in the world, with the second
highest incidence rate after lung cancer. Oxaliplatin (OXA) is a broad-spectrum anti-tumor …

Abstract [FeFe] hydrogenase (H2ase) mimicking complexes containing lipoic and
selenolipoic acid moieties connected to 2‐hydroxy‐1, 3‐dithiopropane and 2‐hydroxy‐1, 3 …