In the biomedical field, researchers are always looking for novel materials with improved
qualities that may be used in a variety of applications, including pharmaceutical …

Chitosan, as a biodegradable and biocompatible polymer, is characterized by anti-microbial
and anti-cancer properties. It lately has received a widespread interest for use as the …

Diabetic cases have increased rapidly in recent years throughout the world. Currently, for
type-1 diabetes mellitus (T1DM), multiple daily insulin (MDI) injections is the most popular …

Abstract N, N, N-trimethyl chitosan (TMC), a quaternized hydrophilic derivative of chitosan
(CHT), outperformed the well-known solubility issues raised by CHT. The excellent …

Chitosan-Fe0 nanoparticles (chitosan-Fe0) were prepared using nontoxic and
biodegradable chitosan as a stabilizer. Batch experiments were conducted to evaluate the …

Intestinal epithelium is a major barrier limiting the absorption of oral insulin owing to the
presence of intercellular tight junctions (TJs). Previous studies proved that carboxymethyl …

Quaternary Trimethyl Chitosan (QTMC) and QTMC-Silver Nanoparticles (QTMC-AgNPs)
have been synthesized, characterized, and tested as antibacterial agents against …

A series of thiol-terminated polyethylene glycol (PEG)-paclitaxel (PTX) derivatives are
designed and synthesized to fabricate PTX-conjugated gold nanoparticles (PTX@ GNPs) …

Novel nanoparticles (NPs) coated with chitosan which allow insulin to be administered orally
were developed. The NPs could transiently and reversibly open the tight junctions in Caco-2 …

Drug-conjugated gold nanoparticles (GNPs), which are generally constructed with many
molecules of thiol-terminated polyethylene glycol (PEG)-drug decorated on their surfaces via …