Hox genes, a highly conserved subgroup of the homeobox superfamily, have crucial roles in
development, regulating numerous processes including apoptosis, receptor signalling …

Large intervening non-coding RNAs (lincRNAs) are pervasively transcribed in the genome,,
yet their potential involvement in human disease is not well understood,. Recent studies of …

Homeobox (HOX) transcription factors, encoded by a subset of homeodomain superfamily
genes, play pivotal roles in many aspects of cellular physiology, embryonic development …

Deleterious inflammation is a primary feature of breast cancer. Accumulating evidence
demonstrates that macrophages, the most abundant leukocyte population in mammary …

Recently, a novel class of transcripts, long non-coding RNAs (lncRNAs), is being identified
at a rapid pace. These RNAs have critical roles in diverse biological processes, including …

Background: The precise details of pancreatic ductal adenocarcinoma (PDAC)
pathogenesis are still insufficiently known, requiring the use of higthroughput methods …

The polycomb group protein B lymphoma Mo-MLV insertion region 1 homolog (Bmi-1) is
dysregulated in various cancers, and its upregulation strongly correlates with an invasive …

We review here the recently emerging relationship between epithelial-mesenchymal
transition (EMT) and breast cancer stem cells (BCSC), and provide analyses of published …

Neuroblastoma is an embryonal malignancy of the sympathetic nervous system.
Spontaneous regression and differentiation of neuroblastoma is observed in a subset of …

The tight junction is a multi-protein complex and is the apical most junctional complex in
certain epithelial and endothelial cells. A great deal of attention has been devoted to the …