Neuromorphic hardware for somatosensory neuroprostheses

E Donati, G Valle - Nature Communications, 2024 - nature.com
In individuals with sensory-motor impairments, missing limb functions can be restored using
neuroprosthetic devices that directly interface with the nervous system. However, restoring …

Nanomaterial-based biohybrid hydrogel in bioelectronics

M Shin, J Lim, J An, J Yoon, JW Choi - Nano Convergence, 2023 - Springer
Despite the broadly applicable potential in the bioelectronics, organic/inorganic material-
based bioelectronics have some limitations such as hard stiffness and low biocompatibility …

Biomimetic computer-to-brain communication enhancing naturalistic touch sensations via peripheral nerve stimulation

G Valle, N Katic Secerovic, D Eggemann… - Nature …, 2024 - nature.com
Artificial communication with the brain through peripheral nerve stimulation shows promising
results in individuals with sensorimotor deficits. However, these efforts lack an intuitive and …

Towards enhanced functionality of vagus neuroprostheses through in silico optimized stimulation

F Ciotti, R John, N Katic Secerovic, N Gozzi… - Nature …, 2024 - nature.com
Bioelectronic therapies modulating the vagus nerve are promising for cardiovascular,
inflammatory, and mental disorders. Clinical applications are however limited by side-effects …

Evoking stable and precise tactile sensations via multi-electrode intracortical microstimulation of the somatosensory cortex

CM Greenspon, G Valle, ND Shelchkova… - Nature Biomedical …, 2024 - nature.com
Tactile feedback from brain-controlled bionic hands can be partially restored via intracortical
microstimulation (ICMS) of the primary somatosensory cortex. In ICMS, the location of …

Modeling foot sole cutaneous afferents: FootSim

N Katic, RK Siqueira, L Cleland, N Strzalkowski, L Bent… - Iscience, 2023 - cell.com
While walking and maintaining balance, humans rely on cutaneous feedback from the foot
sole. Electrophysiological recordings reveal how this tactile feedback is represented in …

Multiparametric non-linear TENS modulation to integrate intuitive sensory feedback

V Bucciarelli, N Gozzi, N Katic, G Aiello… - Journal of Neural …, 2023 - iopscience.iop.org
Objective. Transcutaneous electrical nerve stimulation (TENS) has been recently introduced
in neurorehabilitation and neuroprosthetics as a promising, non-invasive sensory feedback …

Recalibration of neuromodulation parameters in neural implants with adaptive Bayesian optimization

G Aiello, G Valle, S Raspopovic - Journal of Neural Engineering, 2023 - iopscience.iop.org
Objective. Neuromodulation technology holds promise for treating conditions where
physiological mechanisms of neural activity have been affected. To make treatments efficient …

[HTML][HTML] Tessellation of artificial touch via microstimulation of human somatosensory cortex

CM Greenspon, ND Shelchkova, G Valle, TG Hobbs… - bioRxiv, 2023 - ncbi.nlm.nih.gov
When we interact with objects, we rely on signals from the hand that convey information
about the object and our interaction with it. A basic feature of these interactions, the locations …

Electrical stimulation of regenerative peripheral nerve interfaces (RPNIs) induces referred sensations in people with upper limb loss

MA Gonzalez, C Nwokeabia, AK Vaskov… - … on Neural Systems …, 2023 - ieeexplore.ieee.org
Individuals with upper limb loss lack sensation of the missing hand, which can negatively
impact their daily function. Several groups have attempted to restore this sensation through …