Antibiotic perturbations to the gut microbiome

SRS Fishbein, B Mahmud, G Dantas - Nature Reviews Microbiology, 2023 - nature.com
Antibiotic-mediated perturbation of the gut microbiome is associated with numerous
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …

Co-selection of multi-antibiotic resistance in bacterial pathogens in metal and microplastic contaminated environments: An emerging health threat

M Imran, KR Das, MM Naik - Chemosphere, 2019 - Elsevier
Misuse/over use of antibiotics increases the threats to human health since this is a main
reason behind evolution of antibiotic resistant bacterial pathogens. However, metals such as …

Review of emerging contaminants in green stormwater infrastructure: Antibiotic resistance genes, microplastics, tire wear particles, PFAS, and temperature

B Bodus, K O'Malley, G Dieter, C Gunawardana… - Science of the Total …, 2024 - Elsevier
Green stormwater infrastructure is a growing management approach to capturing, infiltrating,
and treating runoff at the source. However, there are several emerging contaminants for …

Persistence and reversal of plasmid-mediated antibiotic resistance

AJ Lopatkin, HR Meredith, JK Srimani, C Pfeiffer… - Nature …, 2017 - nature.com
In the absence of antibiotic-mediated selection, sensitive bacteria are expected to displace
their resistant counterparts if resistance genes are costly. However, many resistance genes …

Effects and relevant mechanisms of non-antibiotic factors on the horizontal transfer of antibiotic resistance genes in water environments: A review

Q Jiang, M Feng, C Ye, X Yu - Science of The Total Environment, 2022 - Elsevier
Antibiotic resistance has created obstacles in the treatment of infectious diseases with
antibiotics. The horizontal transfer of antibiotic resistance genes (ARGs) can exacerbate the …

Predictive biology: modelling, understanding and harnessing microbial complexity

AJ Lopatkin, JJ Collins - Nature Reviews Microbiology, 2020 - nature.com
Predictive biology is the next great chapter in synthetic and systems biology, particularly for
microorganisms. Tasks that once seemed infeasible are increasingly being realized such as …

[HTML][HTML] Dissecting horizontal and vertical gene transfer of antibiotic resistance plasmid in bacterial community using microfluidics

B Li, Y Qiu, Y Song, H Lin, H Yin - Environment International, 2019 - Elsevier
The spread of antibiotic resistance genes (ARGs) has become an emerging threat to the
global health. Although horizontal gene transfer (HGT) is regarded as one of the major …

Insights into the impact of manure on the environmental antibiotic residues and resistance pool

LG Marutescu, M Jaga, C Postolache… - Frontiers in …, 2022 - frontiersin.org
The intensive use of antibiotics in the veterinary sector, linked to the application of manure-
derived amendments in agriculture, translates into increased environmental levels of …

Effect of donor-recipient relatedness on the plasmid conjugation frequency: a meta-analysis

JB Alderliesten, SJN Duxbury, MP Zwart… - BMC microbiology, 2020 - Springer
Background Conjugation plays a major role in the transmission of plasmids encoding
antibiotic resistance genes in both clinical and general settings. The conjugation efficiency is …

Plasmid-mediated antibiotic resistance gene transfer under environmental stresses: Insights from laboratory-based studies

LG Li, T Zhang - Science of The Total Environment, 2023 - Elsevier
Although clinical settings play a major role in the current global dissemination of antibiotic
resistance, once antibiotic resistance bacteria and genes are released into the environment …