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Schistosomiasis in the People's Republic of China: the era of the Three Gorges Dam
The potential impact of the Three Gorges Dam (TGD) on schistosomiasis transmission in
China has invoked considerable global concern. The TGD will result in changes in the water …
China has invoked considerable global concern. The TGD will result in changes in the water …
HDAC inhibitors in parasitic diseases
Parasitic diseases cause significant global morbidity and mortality, particularly in
underdeveloped regions of the world. Malaria alone causes∼ 800 000 deaths each year …
underdeveloped regions of the world. Malaria alone causes∼ 800 000 deaths each year …
Identification of Attractive Drug Targets in Neglected-Disease Pathogens Using an In Silico Approach
Background The increased sequencing of pathogen genomes and the subsequent
availability of genome-scale functional datasets are expected to guide the experimental …
availability of genome-scale functional datasets are expected to guide the experimental …
TDR Targets: a chemogenomics resource for neglected diseases
Abstract The TDR Targets Database (http://tdrtargets. org) has been designed and
developed as an online resource to facilitate the rapid identification and prioritization of …
developed as an online resource to facilitate the rapid identification and prioritization of …
A wake up call for urinary schistosomiasis: reconciling research effort with public health importance
D Rollinson - Parasitology, 2009 - cambridge.org
This review considers the current status of urinary schistosomiasis, caused by infection with
Schistosoma haematobium, and argues that greater research effort and focus are needed to …
Schistosoma haematobium, and argues that greater research effort and focus are needed to …
Schistosoma genomics: new perspectives on schistosome biology and host-parasite interaction
ZG Han, PJ Brindley, SY Wang… - Annual review of …, 2009 - annualreviews.org
Schistosomiasis, caused mainly by Schistosoma japonicum, S. mansoni, and S.
hematobium, remains one of the most prevalent and serious parasitic diseases worldwide …
hematobium, remains one of the most prevalent and serious parasitic diseases worldwide …
A comparative proteomic study of the undeveloped and developed Schistosoma mansoni egg and its contents: the miracidium, hatch fluid and secretions
W Mathieson, RA Wilson - International journal for parasitology, 2010 - Elsevier
The schistosome egg is the key agent responsible both for transmission of the parasite from
human to molluscan host, and is the primary cause of pathogenesis in schistosomiasis …
human to molluscan host, and is the primary cause of pathogenesis in schistosomiasis …
Exposed proteins of the Schistosoma japonicum tegument
The ability of the mammalian blood fluke Schistosoma japonicum to survive in the
inhospitable environment of the mammalian bloodstream can be attributed, at least in part …
inhospitable environment of the mammalian bloodstream can be attributed, at least in part …
RNA Interference in Schistosoma mansoni Schistosomula: Selectivity, Sensitivity and Operation for Larger-Scale Screening
Background The possible emergence of resistance to the only available drug for
schistosomiasis spurs drug discovery that has been recently incentivized by the availability …
schistosomiasis spurs drug discovery that has been recently incentivized by the availability …
Elucidating the transcriptome of Fasciola hepatica—a key to fundamental and biotechnological discoveries for a neglected parasite
Liver flukes of animals are parasitic flatworms (Platyhelminthes: Digenea) of major
socioeconomic importance in many countries. Key representatives, such as Fasciola …
socioeconomic importance in many countries. Key representatives, such as Fasciola …