Eudragit® polymers are polymethacrylates highly used in pharmaceutics for the
development of modified drug delivery systems. They are widely known due to their …

Almost 100 years after the discovery of the Raman scattering phenomenon, related
analytical techniques have emerged as important tools in biomedical sciences. Raman …

Precision medicine is an emerging healthcare delivery approach that considers variability
between patients, such as genetic makeups, in contrast to the current one-size-fits-all …

Hot melt extrusion has been a widely used process in the pharmaceutical area for three
decades. In this field, it is important to optimize the formulation in order to meet specific …

Application of amorphous solid dispersions (ASDs) is considered one of the most promising
approaches to increase the dissolution rate and extent of bioavailability of poorly water …

Hot melt extrusion (HME) can be used to produce amorphous solid dispersions (ASDs) at
temperatures below the drug's melting point if the drug and polymer exhibit melting point …

Newly developed active pharmaceutical ingredients (APIs) are often poorly soluble in water.
As a result the bioavailability of the API in the human body is reduced. One approach to …

The understanding of materials and processes is a requirement when it comes to build
quality into pharmaceutical products. This can be achieved through the development of …

This research aimed to compare two solvent-based methods for the preparation of
amorphous solid dispersions (ASDs) made up of poorly soluble spironolactone and poly …

Co-amorphous solid dispersion (C-ASD) systems have attracted great attention to improve
the solubility of poorly soluble drugs, but the selection of an appropriate stabilizer to stabilize …