The art of natural product total synthesis is closely associated with two major determinants:
the development/application of novel chemical reactions and the innovation in strategic use …

Covering: 2016 to 2023 The synthetic chemistry community is always in pursuit of efficient
routes to natural products. Among the many available general strategies, skeletal …

The synthesis of nitrogen-containing heterocycles, including natural alkaloids and other
compounds presenting different types of biological activities have proved to be successful …

Abstract 2, 3, 3‐Trisubstituted indolenine constitutes an integral part of many biologically
important monoterpene indole alkaloids. We report herein an unprecedented access to this …

The diastereoselective assembly of spiroindolenines via a synergistic scandium/gold-
catalyzed dearomative spiroannulation is herein described. This protocol offers access to a …

Chiral sulfinamides are among the best known chiral auxiliaries in the stereoselective
synthesis of amines and their derivatives. The most extensively used enantiopure tert …

In this study, we accomplished a de novo synthesis of the bisindole alkaloid geissolosimine.
Geissoschizoline, the north fragment of geissolosimine, was first prepared in 15 steps …

The iboga alkaloids are promising antiaddictive and neuroregeneration candidates for
medical treatment. There is a lack of studies for C20-epi iboga alkaloids due to the synthetic …

N-Sulfinyl metalloenamines, generated by deprotonating α-linear N-tert-butanesulfinyl
ketimines, reacted with nitroalkenes via stereoselective conjugate addition to give Michael …

The formation of chiral amine intermediates with chiral tert-butanesulfinamide and their
applications in asymmetric natural product synthesis in recent years are summarized. tert …