Nanotechnology for multimodal synergistic cancer therapy

W Fan, B Yung, P Huang, X Chen - Chemical reviews, 2017 - ACS Publications
The complexity, diversity, and heterogeneity of tumors seriously undermine the therapeutic
potential of treatment. Therefore, the current trend in clinical research has gradually shifted …

Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy

Z Zhou, J Song, L Nie, X Chen - Chemical society reviews, 2016 - pubs.rsc.org
The reactive oxygen species (ROS)-mediated mechanism is the major cause underlying the
efficacy of photodynamic therapy (PDT). The PDT procedure is based on the cascade of …

Upconversion luminescent materials: advances and applications

J Zhou, Q Liu, W Feng, Y Sun, F Li - Chemical reviews, 2015 - ACS Publications
Luminescence-based techniques continue to attract considerable attention due not only to
their current range of applications but also to their wide potential in the fields of optical …

Nanoparticles in photodynamic therapy

SS Lucky, KC Soo, Y Zhang - Chemical reviews, 2015 - ACS Publications
Cancer accounted for 7.6 million deaths (around 13% of all deaths) worldwide in 2008.(1)
Almost 13 million cancer cases are newly diagnosed every year, and deaths are projected to …

Overcoming the Achilles' heel of photodynamic therapy

W Fan, P Huang, X Chen - Chemical Society Reviews, 2016 - pubs.rsc.org
Photodynamic therapy (PDT) has been applied to treat a wide range of medical conditions,
including wet age-related macular degeneration psoriasis, atherosclerosis, viral infection …

[HTML][HTML] Upconversion nanoparticles: design, nanochemistry, and applications in theranostics

G Chen, H Qiu, PN Prasad, X Chen - Chemical reviews, 2014 - ACS Publications
Theranostics is a concept of integrating imaging and therapy into a single platform for use in
the next generation of personalized medicine to meet the challenges in modern health …

Nanochemistry and nanomedicine for nanoparticle-based diagnostics and therapy

G Chen, I Roy, C Yang, PN Prasad - Chemical reviews, 2016 - ACS Publications
Nanoparticles are generally defined as any particulate material for which at least one
dimension lies in the range of 1− 100 nm. 1− 3 They can exist in various shapes, such as …

Nanomaterials for theranostics: recent advances and future challenges

EK Lim, T Kim, S Paik, S Haam, YM Huh… - Chemical reviews, 2015 - ACS Publications
In 2004, the US Food and Drug Administration (FDA) released an important report entitled
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …

Lanthanide nanoparticles: from design toward bioimaging and therapy

H Dong, SR Du, XY Zheng, GM Lyu, LD Sun… - Chemical …, 2015 - ACS Publications
Lanthanides refer to the 15 elements located at the sixth period and IIIB group in the periodic
table, ranging from lanthanum to lutetium, with the electronic configuration of [Xe] 4f n–1 5d …

Recent progress in rare earth micro/nanocrystals: soft chemical synthesis, luminescent properties, and biomedical applications

S Gai, C Li, P Yang, J Lin - Chemical reviews, 2014 - ACS Publications
Luminescent materials, also called phosphors, are defined as solids that can absorb and
convert certain types of energy into radiation of light.(1) Among all kinds of phosphors, rare …