Connexins are ubiquitous channel forming proteins that assemble as plasma membrane
hemichannels and as intercellular gap junction channels that directly connect cells. In the …

▪ Abstract Many neurons in the mammalian central nervous system communicate through
electrical synapses, defined here as gap junction–mediated connections. Electrical …

Neurons that Fire Together Also Conspire Together: Is Normal Sleep Circuitry Hijacked to
Generate Epilepsy?: Neuron Skip to Main Content Skip to Main Menu Advertisement …

Modulation of synaptic transmission and brain microcirculation are new roles ascribed to
astrocytes in CNS function. A mechanism by which astrocytes modify neuronal activity in the …

Astrocytes contribute to neurotransmission through a variety of mechanisms ranging from
synapse isolation to active signaling. Astroglial involvement in neurophysiology has been …

Several new findings have emphasized the role of neuron‐specific gap junction proteins
(connexins) and electrical synapses in processing sensory information and in synchronizing …

Background Chemotherapy‐induced peripheral neuropathy is a serious side effect in cancer
treatment, a major manifestation being neuropathic pain that can be debilitating and can …

Epileptic seizures are characterized by periods of hypersynchronous, hyperexcitability within
brain networks. Most seizures involve two stages: an initial tonic phase, followed by a longer …

Recently, great interest has been shown in understanding the functional roles of specific gap
junction proteins (connexins) in brain, lens, retina, and elsewhere. Some progress has been …

Oscillatory activity is widespread in dynamic neuronal networks. The main paradigm for the
origin of periodicity consists of specialized pacemaking elements that synchronize and drive …