The central nucleus of the amygdala and the construction of defensive modes across the threat-imminence continuum

JM Moscarello, MA Penzo - Nature Neuroscience, 2022 - nature.com
In nature, animals display defensive behaviors that reflect the spatiotemporal distance of
threats. Laboratory-based paradigms that elicit specific defensive responses in rodents have …

Prefrontal–hippocampal interactions in episodic memory

H Eichenbaum - Nature Reviews Neuroscience, 2017 - nature.com
The roles of the hippocampus and prefrontal cortex (PFC) in memory processing—
individually or in concert—are a major topic of interest in memory research. These brain …

[HTML][HTML] Don't fear 'fear conditioning': Methodological considerations for the design and analysis of studies on human fear acquisition, extinction, and return of fear

TB Lonsdorf, MM Menz, M Andreatta… - Neuroscience & …, 2017 - Elsevier
The so-called 'replicability crisis' has sparked methodological discussions in many areas of
science in general, and in psychology in particular. This has led to recent endeavours to …

Behavioral and neurobiological mechanisms of pavlovian and instrumental extinction learning

ME Bouton, S Maren, GP McNally - Physiological reviews, 2021 - journals.physiology.org
This article reviews the behavioral neuroscience of extinction, the phenomenon in which a
behavior that has been acquired through Pavlovian or instrumental (operant) learning …

Context processing and the neurobiology of post-traumatic stress disorder

I Liberzon, JL Abelson - Neuron, 2016 - cell.com
Progress in clinical and affective neuroscience is redefining psychiatric illness as
symptomatic expression of cellular/molecular dysfunctions in specific brain circuits. Post …

Learning, reward, and decision making

JP O'Doherty, J Cockburn… - Annual review of …, 2017 - annualreviews.org
In this review, we summarize findings supporting the existence of multiple behavioral
strategies for controlling reward-related behavior, including a dichotomy between the goal …

The contextual brain: implications for fear conditioning, extinction and psychopathology

S Maren, KL Phan, I Liberzon - Nature reviews neuroscience, 2013 - nature.com
Contexts surround and imbue meaning to events; they are essential for recollecting the past,
interpreting the present and anticipating the future. Indeed, the brain's capacity to …

The neurobiology of fear generalization

A Asok, ER Kandel, JB Rayman - Frontiers in behavioral …, 2019 - frontiersin.org
The generalization of fear memories is an adaptive neurobiological process that promotes
survival in complex and dynamic environments. When confronted with a potential threat, an …

Sex differences in fear responses: Neural circuits

EP Bauer - Neuropharmacology, 2023 - Elsevier
Women have increased vulnerability to PTSD and anxiety disorders compared to men.
Understanding the neurobiological underpinnings of these disorders is critical for identifying …

Neurobiology of Pavlovian fear conditioning

S Maren - Annual review of neuroscience, 2001 - annualreviews.org
▪ Abstract Learning the relationships between aversive events and the environmental stimuli
that predict such events is essential to the survival of organisms throughout the animal …