An insight on medicinal attributes of 1, 2, 4-triazoles

R Aggarwal, G Sumran - European journal of medicinal chemistry, 2020 - Elsevier
The present review aims to summarize the pharmacological profile of 1, 2, 4-triazole, one of
the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant …

Recent advances in 1, 2, 4‐triazole scaffolds as antiviral agents

SA El‐Sebaey - ChemistrySelect, 2020 - Wiley Online Library
In recent years, severe viral infections have emerged, and antiviral chemotherapeutic agents
are not adequately effective in curing these infections, leading to serious human diseases …

[HTML][HTML] Mechanism-based approaches of 1, 3, 4 thiadiazole scaffolds as potent enzyme inhibitors for cytotoxicity and antiviral activity

D Kumar, H Kumar, V Kumar, A Deep, A Sharma… - Medicine in Drug …, 2023 - Elsevier
Significant progress in understanding cancer pathogenesis, it remains one of the leading
causes of death after cardiovascular diseases. Similarly viral infections have emerged from …

[HTML][HTML] New Schiff bases derived from dimethylpyridine-1, 2, 4-triazole hybrid as cytotoxic agents targeting gastrointestinal cancers: Design, synthesis, biological …

M Strzelecka, B Wiatrak, P Jawień, Ż Czyżnikowska… - Bioorganic …, 2023 - Elsevier
In this research, a series of novel hybrid structures of dimethylpyridine-1, 2, 4-triazole Schiff
bases were designed, synthesized, and evaluated for their in vitro cytotoxic potency on …

Breaking Down the Barriers to a Natural Antiviral Agent: Antiviral Activity and Molecular Docking of Erythrina speciosa Extract, Fractions, and the Major Compound

NM Fahmy, E Al‐Sayed, S Moghannem… - Chemistry & …, 2020 - Wiley Online Library
The in vitro cytotoxic activity in Vero cells and the antiviral activity of Erythrina speciosa
methanol extract, fractions, and isolated vitexin were studied. The results revealed that E …

Antiviral activity of 1, 2, 4-triazole derivatives (microreview)

NV Simurova, OI Maiboroda - Chemistry of heterocyclic compounds, 2021 - Springer
Antiviral activity of 1,2,4-triazole derivatives (microreview) | Chemistry of Heterocyclic
Compounds Skip to main content Advertisement Springer Nature Link Account Menu Find a …

Emerging synthetic strategies and pharmacological insights of 1, 3, 4-thiadiazole derivatives: A comprehensive review

D Kumar, N Aggarwal, V Kumar, H Chopra… - Future Medicinal …, 2024 - Taylor & Francis
This review meticulously examines the synthesis techniques for 1, 3, 4-thiadiazole
derivatives, focusing on cyclization, condensation reactions and functional group …

Development of industrial production technology with determination of the quality of a soft medicine «Vetmikoderm» for veterinary

MV Ogloblina, IV Bushueva, VP Martynyshyn… - Farmatsevtychnyi …, 2023 - pharmj.org.ua
It is well known, that 1, 2, 4–triazole derivatives have a wide range of biological properties,
showing little toxicity. Original modeling of 1, 2, 4-triazole derivatives allows obtaining new …

Investigation of the Properties of 1, 2, 4‐Triazole‐3‐thione Schiff Base Derivatives by Urease Inhibition as Therapeutic or Agrochemical Candidate Molecules

G Zehir Kirkbir, E Gultekin, Y Kolcuoglu… - …, 2024 - Wiley Online Library
With the production of bacterial urease, bacteria can provide the best conditions for
colonization and survival of the stomach in acidic environment. Due to this reproductive …

Diacetoxy iodobenzene mediated regioselective synthesis and characterization of novel [1, 2, 4] triazolo [4, 3-a] pyrimidines: apoptosis inducer, antiproliferative …

R Kamal, R Kumar, V Kumar, JK Bhardwaj… - Journal of …, 2021 - Taylor & Francis
Prompt and regioselective synthesis of eleven novel [1, 2, 4] triazolo [4, 3-a] pyrimidines 2a-
2k, via intramolecular oxidative-cyclization of 2-(2-arylidenehydrazinyl)-4-methyl-6 …